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388 Characterisation of patients with systemic lupus erythematosus who were admitted to a university hospital in bogota-colombia between 2008 and 2016
  1. J Aponte1,
  2. A Cartagena1,
  3. J Carrizosa2,
  4. A Sanchez3,
  5. MT Ospina5,
  6. C Gamboa4 and
  7. R Cervera6
  1. 1Hospital Universitario de la Samaritana – Universidad de La Sabana, Medicina Interna, Bogota, Colombia
  2. 2Universidad del Rosario, Cuidado critico, Bogota, Colombia
  3. 3Hospital universitario de la samaritana, Medicina interna – Cuidado intensivo, Bogota, Colombia
  4. 4Hospital universitario de la samaritana, Cuidado critico, Bogota, Colombia
  5. 5Universidad de la Sabana, Medicina – Pregrado, Bogota, Colombia
  6. 6Senior y Jefe del Servicio de Enfermedades Autoinmunes del Hospital Clínic de Barcelona, Enfermedades autoinmunes, Madrid, Spain

Abstract

Background and aims Systemic lupus erythematosus is one of the most prevalent autoimmune disease, and it is associated with many complications, morbidity and mortality. The mortality in these patients is related with immune activity, infectious complication and a direct effect of pharmacology therapy. All these factors result in target organ injury.

Methods A retrospective-descriptive study of patients admitted to the intensive care unit of the Hospital Universitario de la Samaritana between 2008 and 2016 in the city of Bogota was performed. The aim of this study was to characterise the clinical, demographic and paraclinical features of patients with systemic lupus erythematosus.

Results 56 cases were collected, most of the patients were relatively young with an average age of 40.7 years (SD ±17.7 y/o). These people were mainly female (71% vs 29%), the immune activity was measure with score SELENA SLEDAI with average 16.5 (SD±4.3), in the analysis of target organ 69% of patient had lupus nephritis, 42% haematological commitment, 28% lung injury, 17% neurological complications and 48.25 had infectious process. When it comes to the days of mechanical ventilation, the average was 9 (SD ±10), days of ICU stay 13.7 (SD ±14.3) and finally the mortality was 39.2%.

Conclusions At ICU of our hospital, the prevalence of patients with systemic lupus erythematosus tends to be more frequent than in other series reported, this information may be useful in future studies and can also reduce complications and mortality in this population.

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