Lupus Science & Medicine: 9 (1)

Animal models

Original research:
Systemic blockade of proBDNF inhibited the expansion and altered the transcriptomic expression in CD3⁺B220⁺ cells in MRL/lpr lupus mice
(29 December, 2022)
An-Hui Zha, Cong Luo, Wei-Yun Shen, Di Fu, Ru-Ping Dai

Brief communication

Black patients with cutaneous lupus are associated with positive family history of cutaneous lupus and systemic lupus (6 December, 2022)
Heejo Keum, L Steven Brown, Benjamin F Chong
Teratogenic medication use associated with favourable odds of contraception counselling in a cohort of women with systemic lupus erythematosus at a large tertiary academic medical centre (23 November, 2022)
Shruti Chandramouli, Carolina Alvarez, Tessa R Englund, R Gina Silverstein, Saira Z Sheikh
Changes in cardiorespiratory function and fatigue following 12 weeks of exercise training in women with systemic lupus erythematosus: a pilot study (11 October, 2022)
Sarfaraz Hasni, Li Rebekah Feng, Marquis Chapman, Sarthak Gupta, Anam Ahmad, Adam Munday, Mir Ali Mazhar, Xiaobai Li, Shajia Lu, Wanxia Li Tsai, Massimo Gadina, Michael Davis, Jun Chu, Zerai Manna, Shuichiro Nakabo, Mariana J Kaplan, Leorey Saligan, Randall Keyser, Leighton Chan, Lisa M K Chin
Antibodies to FXa and thrombin in patients with SLE differentially regulate C3 and C5 cleavage (25 August, 2022)
Thomas McDonnell, Raj Amarnani, Carina Spicer, Hajar Jbari, Charis Pericleous, Valentina A Spiteri, Chris Wincup, Bahar Artim-Esen, Ian Mackie, Marina Botto, Anisur Rahman, Ian Giles
Peripheral blood T-cell subset and its clinical significance in lupus nephritis patients (16 August, 2022)
Huijing Wang, Lan Lan, Jianghua Chen, Liang Xiao, Fei Han
Truncated isoforms of GPSM2 containing the GoLoco motif region promote CD4⁺ T-cell migration in SLE
(8 August, 2022)
Ruth L Esser, Carolin Brück, Jan Thiele, Viktoria Golumba-Nagy, Anja Meyer, Eva Steinbach-Knödgen, Shuaifeng Yan, Carola tho Pesch, David Stahl, Joanna Schiller, David M Kofler
Immune complex–driven neutrophil activation and BAFF release: a link to B cell responses in SLE (19 July, 2022)
Ting Wang, Andrew Vasconcellos, John Marken, Sladjana Skopelja-Gardner, Christian Lood, Natalia V Giltiay
Cytokine autoantibodies in SARS-CoV-2 prepandemic and intrapandemic samples from an SLE cohort (7 April, 2022)
May Y Choi, Ann Elaine Clarke, Katherine Buhler, Michelle Jung, Hannah Mathew, Meifeng Zhang, Francesca S Cardwell, Heather Waldhauser, Marvin J Fritzler
LLDAS (lupus low disease activity state) and/or remission are associated with less damage accrual in patients with systemic lupus erythematosus from a primarily Mestizo population: data from the Almenara Lupus Cohort (22 February, 2022)
Manuel Francisco Ugarte-Gil, Rocio Violeta Gamboa-Cardenas, Cristina Reátegui-Sokolova, Victor Román Pimentel-Quiroz, Mariela Medina, Claudia Elera-Fitzcarrald, Francisco Zevallos, Cesar Augusto Pastor-Asurza, Jeniffer Lofland, Federico Zazzetti, Chetan S Karyekar, Graciela S Alarcón, Risto Alfredo Perich-Campos
Association of COVID-19 pandemic-related concern and health routine changes with functioning among individuals with systemic lupus erythematosus (17 February, 2022)
Laura C Plantinga, Courtney Hoge, Charmayne Dunlop-Thomas, Brad D Pearce, S Sam Lim, Cristina Drenkard, C Barrett Bowling

Biomarker studies

Original research: Autoantibodies associated with systemic sclerosis in three autoimmune diseases imprinted by type I interferon gene dysregulation: a comparison across SLE, primary Sjögren’s syndrome and systemic sclerosis (29 December, 2022)
Rama Andraos, Awais Ahmad, Per Eriksson, Örjan Dahlström, Lina Wirestam, Charlotte Dahle, Roger Hesselstrand, Anders A Bengtsson, Andreas Jönsen, Kristofer Andréasson, Christopher Sjöwall
Original research: Associations between circulating interferon and kynurenine/tryptophan pathway metabolites: support for a novel potential mechanism for cognitive dysfunction in SLE (16 November, 2022)
Erik W Anderson, Ying Jin, Andrew Shih, Arnon Arazi, Sara Goodwin, Julien Roeser, Richard A Furie, Cynthia Aranow, Bruce Volpe, Betty Diamond, Meggan Mackay
Original research: Urine proteomic insights from the belimumab in lupus nephritis trial (27 September, 2022)
Emma Weeding, Andrea Fava, Chandra Mohan, Laurence Magder, Daniel Goldman, Michelle Petri
Original research: Erythrocyte complement receptor 1 (ECR1) and erythrocyte-bound C4d (EC4d) in the prediction of poor pregnancy outcomes in systemic lupus erythematosus (SLE) (5 September, 2022)
John Conklin, Michael Golpanian, Alexis Engel, Peter Izmirly, H Michael Belmont, Thierry Dervieux, Jill P Buyon, Roberta Vezza Alexander
Original research: Novel immunoprofiling method for diagnosing SLE and evaluating therapeutic response (23 June, 2022)
Jan-Mou Lee, Ming-Huang Chen, Kai-Yuan Chou, Yee Chao, Ming-Han Chen, Chang-Youh Tsai
Original research:
Phenotypical changes and clinical significance of CD4⁺/CD8⁺ T cells in SLE
(22 June, 2022)
Shiwen Yuan, Yanting Zeng, Jiawei Li, Cuicui Wang, Weinian Li, Zhixiang He, Jinghua Ye, Fangfei Li, Yi Chen, Xiaojun Lin, Na Yu, Xiaoyan Cai
Original research: Predictors of treatment response in a lupus nephritis population: lessons from the Aspreva Lupus Management Study (ALMS) trial (31 May, 2022)
Stephen McDonald, Sean Yiu, Li Su, Caroline Gordon, Matt Truman, Laura Lisk, Neil Solomons, Ian N Bruce
Original research: Influence of hydroxychloroquine blood levels on adhesion molecules associated with endothelial dysfunction in patients with systemic lupus erythematosus (24 March, 2022)
Serena Fasano, Michele Iudici, Melania Alessia Coscia, Valentina Messiniti, Alessia Borgia, Rosella Tirri, Francesco Ciccia
Original research: Inflammatory markers in saliva and urine reflect disease activity in patients with systemic lupus erythematosus (4 March, 2022)
Guillermo Ruacho, Ronaldo Lira-Junior, Iva Gunnarsson, Elisabet Svenungsson, Elisabeth A Boström
Original research: Type 1 interferon status in systemic lupus erythematosus: a longitudinal analysis (23 February, 2022)
Melissa Northcott, Sarah Jones, Rachel Koelmeyer, Julie Bonin, Fabien Vincent, Rangi Kandane-Rathnayake, Alberta Hoi, Eric Morand

Childhood lupus

Original research: Pharmacokinetics of hydroxychloroquine in paediatric lupus: data from a novel, direct-to-family clinical trial (3 November, 2022)
Stephen J Balevic, Rachel Randell, Daniel Weiner, Claire Beard, Laura Eve Schanberg, Christoph P Hornik, Michael Cohen-Wolkowiez, Daniel Gonzalez
Original research: Clinical measurement of lupus nephritis activity is inferior to biomarker-based activity assessment using the renal activity index for lupus nephritis in childhood-onset systemic lupus erythematosus (13 May, 2022)
Najla Aljaberi, Scott E Wenderfer, Arjun Mathur, Tingting Qiu, Steffy Jose, Angela Merritt, James Rose, Prasad Devarajan, Bin Huang, Hermine Brunner
Original research: “There’s so much to be done”: a qualitative study to elucidate research priorities in childhood-onset systemic lupus erythematosus (31 March, 2022)
Laura Cannon, Anne Caliendo, Aimee Hersh, Andrea M Knight
Original research: Nailfold capillary scleroderma pattern may be associated with disease damage in childhood-onset systemic lupus erythematosus: important lessons from longitudinal follow-up (9 February, 2022)
Dieneke Schonenberg-Meinema, Sandy C Bergkamp, Amara Nassar-Sheikh Rashid, Mariken P Gruppen, Maritza A Middelkamp-Hup, Wineke Armbrust, Koert Dolman, A Elisabeth Hak, Petra C E Hissink Muller, Marieke van Onna, Joost F Swart, Taco W Kuijpers, Sylvia S M Kamphuis, Vanessa Smith, J Merlijn van den Berg

Clinical trials and drug discovery

Original research: Utility of the ACR-1997, SLICC-2012 and EULAR/ACR-2019 classification criteria for systemic lupus erythematosus: a single-centre retrospective study (8 September, 2022)
Wentian Lu, Ying Zhong, Chenghua Weng, Qing Wang, Mei Tang, Zhichun Liu, Leixi Xue
Original research: Safety, immunological effects and clinical response in a phase I trial of umbilical cord mesenchymal stromal cells in patients with treatment refractory SLE (12 July, 2022)
Diane L Kamen, Caroline Wallace, Zihai Li, Megan Wyatt, Crystal Paulos, Chungwen Wei, Hongjun Wang, Bethany J Wolf, Paul J Nietert, Gary Gilkeson
Original research: Sirolimus versus tacrolimus for systemic lupus erythematosus treatment: results from a real-world CSTAR cohort study (3 January, 2022)
Nan Jiang, Mengtao Li, Hongfeng Zhang, Xinwang Duan, Xiaofeng Li, Yongfei Fang, Hongbin Li, Pingting Yang, Hui Luo, Yanhong Wang, Liying Peng, Jiuliang Zhao, Chanyuan Wu, Qian Wang, Xinping Tian, Yan Zhao, Xiaofeng Zeng

Co-morbidities

Original research: Impact of severe infections in SLE: an observational study from the Spanish national registry (25 October, 2022)
Victor Moreno-Torres, María Martínez-Urbistondo, Angela Gutiérrez-Rojas, Raquel Castejón, Enrique Sánchez, Jorge Calderón-Parra, Pedro Durán-del Campo, Pablo Tutor, Susana Mellor-Pita, José Vázquez-Comendador, Juan A Vargas-Núñez, Guillermo Ruiz-Irastorza
Original research: Major infections in newly diagnosed systemic lupus erythematosus: an inception cohort study (30 August, 2022)
Haiting Wang, Yuhong Zhou, Liqin Yu, Wanlong Wu, Liling Zhao, Shikai Geng, Fangfang Sun, Danting Zhang, Nan Shen, Yi Chen, Shuang Ye
Original research: Red blood cell-derived phosphatidylserine positive extracellular vesicles are associated with past thrombotic events in patients with systemic erythematous lupus (8 March, 2022)
Stephan Hasse, Anne-Sophie Julien, Anne-Claire Duchez, Chenqi Zhao, Eric Boilard, Paul R Fortin, Sylvain G Bourgoin

Cutaneous lupus

Original research: Depression, stigma and social isolation: the psychosocial trifecta of primary chronic cutaneous lupus erythematosus, a cross-sectional and path analysis (11 August, 2022)
Cristina Drenkard, Kristina A Theis, Timothy T Daugherty, Charles G Helmick, Charmayne Dunlop-Thomas, Gaobin Bao, Laura Aspey, Tené T Lewis, S Sam Lim

Dialogue

Dialogue: Hydroxychloroquine pharmacokinetic (PK) and exposure response in pregnancies with systemic lupus erythematosus: the importance of adherence for neonatal outcome (7 January, 2022)
Bonnie Bermas, Nathalie Costedoat-Chalumeau

Epidemiology and outcomes

Original research: Evaluating disease control following belimumab treatment in patients with SLE enrolled in the US OBSErve study (30 November, 2022)
Jacob N Hunnicutt, Jolyon Fairburn-Beech, Mary Elizabeth Georgiou, Anna Richards, Yun Irene Gregan, Holly Quasny, Deven Chauhan
Original research: Retinal toxicity in a multinational inception cohort of patients with systemic lupus on hydroxychloroquine (17 November, 2022)
Celline C Almeida-Brasil, John G Hanly, Murray Urowitz, Ann Elaine Clarke, Guillermo Ruiz-Irastorza, Caroline Gordon, Rosalind Ramsey-Goldman, Michelle A Petri, Ellen M Ginzler, Daniel J Wallace, Sang-Cheol Bae, Juanita Romero-Diaz, Mary-Anne Dooley, Christine Peschken, David Isenberg, Anisur Rahman, Susan Manzi, Søren Jacobsen, S Sam Lim, Ronald van Vollenhoven, Ola Nived, Andreas Jönsen, Diane L Kamen, Cynthia Aranow, Jorge Sánchez-Guerrero, Dafna D Gladman, Paul R Fortin, Graciela S Alarcon, Joan T Merrill, Kenneth Kalunian, Manuel Ramos-Casals, Kristjan Steinsson, A Zoma, Anca D Askanase, Munther Khamashta, Ian N Bruce, Murat Inanc, Luck Lukusa, Sasha Bernatsky
Original research: Health information use by patients with systemic lupus erythematosus (SLE) pre and during the COVID-19 pandemic (25 October, 2022)
Francesca S Cardwell, Susan J Elliott, Ricky Chin, Yvan St Pierre, May Y Choi, Murray B Urowitz, Guillermo Ruiz-Irastorza, Sasha Bernatsky, Daniel J Wallace, Michelle A Petri, Susan Manzi, Sang-Cheol Bae, Jung-Min Shin, Anselm Mak, Jiacai Cho, Christine A Peschken, Rosalind Ramsey-Goldman, Paul R Fortin, John G Hanly, Bernardo A Pons-Estel, Romina Nieto, Anca D Askanase, Juanita Romero-Diaz, Marta Mosca, Ian N Bruce, Leigha Rowbottom, Leanne Mielczarek, Karin Tse, Ashley Marion, Juan Carlos Cáhiz-González, Teresa G Cattoni, Alain Cornet, Ann Elaine Clarke
Original research: Association of one-point glucocorticoid-free status with chronic damage and disease duration in systemic lupus erythematosus: a cross-sectional study (27 September, 2022)
Ken-ei Sada, Yu Katayama, Yosuke Asano, Keigo Hayashi, Yoshia Miyawaki, Keiji Ohashi, Eri Katsuyama, Takayuki Katsuyama, Mariko Takano-Narazaki, Yoshinori Matsumoto, Ryusuke Yoshimi, Yasuhiro Shimojima, Shigeru Ohno, Hiroshi Kajiyama, Kunihiro Ichinose, Shuzo Sato, Michio Fujiwara, Nobuyuki Yajima
Original research: Adverse pregnancy outcomes in women with systemic lupus erythematosus: can we improve predictions with machine learning? (14 September, 2022)
Melissa J Fazzari, Marta M Guerra, Jane Salmon, Mimi Y Kim
Original research: Generation of evidence supporting the content validity of SF-36, FACIT-F, and LupusQoL, and novel patient-reported symptom items for use in patients with systemic lupus erythematosus (SLE) and SLE with lupus nephritis (LN) (25 August, 2022)
Rebecca Williams-Hall, Pamela Berry, Nicola Williamson, Melissa Barclay, Anna Roberts, Adam Gater, Chloe Tolley, Helena Bradley, Amy Ward, Elizabeth Hsia, Qing Zuraw, Patricia DeLong, Zahi Touma, Vibeke Strand
Original research: Medium-term impact of the SARS-CoV-2 mRNA vaccine against disease activity in patients with systemic lupus erythematosus (12 August, 2022)
Tsuneyasu Yoshida, Hideaki Tsuji, Akira Onishi, Yudai Takase, Mirei Shirakashi, Hideo Onizawa, Ryosuke Hiwa, Koji Kitagori, Shuji Akizuki, Ran Nakashima, Masao Tanaka, Hajime Yoshifuji, Akio Morinobu
Original research: Intermittent and Persistent Type 2 lupus: patient perspectives on two distinct patterns of Type 2 SLE symptoms (5 August, 2022)
Amanda M Eudy, Jennifer L Rogers, Amy Corneli, Kevin McKenna, Mithu Maheswaranathan, David S Pisetsky, Lisa G Criscione-Schreiber, Jayanth Doss, Rebecca E Sadun, Kai Sun, Megan E B Clowse
Original research: Patient and healthcare team recommended medication adherence strategies for hydroxychloroquine: results of a qualitative study informing intervention development (1 August, 2022)
Shivani Garg, Betty Chewning, David Gazeley, Shelby Gomez, Noah Kaitz, Amanda C Weber, Ann Rosenthal, Christie Bartels
Original research: Immunogenicity of the third and fourth BNT162b2 mRNA COVID-19 boosters and factors associated with immune response in patients with SLE and rheumatoid arthritis (28 July, 2022)
Theerada Assawasaksakul, Seelwan Sathitratanacheewin, Preeyaporn Vichaiwattana, Nasamon Wanlapakorn, Yong Poovorawan, Yingyos Avihingsanon, Nawaporn Assawasaksakul, Wonngarm Kittanamongkolchai
Social Factors, Epigenomics and Lupus in African American Women (SELA) Study: protocol for an observational mechanistic study examining the interplay of multiple individual and social factors on lupus outcomes in a health disparity population (29 June, 2022)
Emily L Vara, Carl D Langefeld, Bethany J Wolf, Timothy D Howard, Gregory A Hawkins, Queen Quet, Lee H Moultrie, L Quinnette King, Ivan D Molano, Stephanie L Bray, Lori Ann Ueberroth, S Sam Lim, Edith M Williams, Diane L Kamen, Paula S Ramos
Original research: Impact of low-dose acetylsalicylic acid on pregnancy outcome in systemic lupus erythematosus: results from a multicentre study (14 June, 2022)
Chiara Tani, Dina Zucchi, Isabell Haase, Maria Gerosa, Maddalena Larosa, Lorenzo Cavagna, Alessandra Bortoluzzi, Francesca Crisafulli, Johanna Mucke, Francesca A L Strigini, Laura Baglietto, Marco Fornili, Francesca Monacci, Elena Elefante, Roberta Erra, Elisa Bellis, Melissa Padovan, Laura Andreoli, Lavinia Agra Coletto, Giovanni Zanframundo, Marcello Govoni, Luca Iaccarino, Angela Tincani, Andrea Doria, Rebecca Fischer-Betz, Marta Mosca
Original research: Glucocorticoid discontinuation in patients with SLE with prior severe organ involvement: a single-center retrospective analysis (2 June, 2022)
Takehiro Nakai, Sho Fukui, Yukihiko Ikeda, Masei Suda, Hiromichi Tamaki, Masato Okada
Original research: Real-world burden of systemic lupus erythematosus in the USA: a comparative cohort study from the Medical Expenditure Panel Survey (MEPS) 2016–2018 (24 May, 2022)
Shannon Grabich, Eileen Farrelly, Robert Ortmann, Michael Pollack, Sandra Sze-jung Wu
Original research: Predictors of refractory risk in systemic lupus erythematosus-related thrombocytopenia: a dual-centre retrospective study (20 May, 2022)
Kaisheng Su, Hao Cheng, Zhifang Jia, Yi Yuan, Huidan Yang, Qi Gao, Zhenyu Jiang, Hongyan Wen, Jing Jiang
Original research: Risk factors of disease flares in a Chinese lupus cohort with low-grade disease activity (20 May, 2022)
Fangfang Sun, Liling Zhao, Haiting Wang, Danting Zhang, Jie Chen, Xiaodong Wang, Ting Li, Shuang Ye
Original research: Improving patient pathways for systemic lupus erythematosus: a multistakeholder pathway optimisation study (13 May, 2022)
Aurelien Schlencker, Laurent Messer, Marc Ardizzone, Gilles Blaison, Olivier Hinschberger, Etienne Dahan, Christelle Sordet, Julia Walther, Anne Dory, Maria Gonzalez, Stéphanie Kleinlogel, Aurélia Bramont-Nachman, Lionel Barrand, Isabelle Payen-Revol, Jean Sibilia, Thierry Martin, Laurent Arnaud
Original research: Coping with systemic lupus erythematosus in patients’ words (13 May, 2022)
Alain Cornet, Davide Mazzoni, Angela Edwards, Dario Monzani, Gabriella Pravettoni, Jeanette Andersen, Marta Mosca
Original research: Severe flares are associated with a poorer health-related quality of life (HRQoL) in patients with SLE: data from the Almenara Lupus Cohort (29 March, 2022)
Manuel Francisco Ugarte-Gil, Rocio Violeta Gamboa-Cardenas, Cristina Reátegui-Sokolova, Victor Román Pimentel-Quiroz, Mariela Medina, Claudia Elera-Fitzcarrald, Francisco Zevallos, Cesar Augusto Pastor-Asurza, Federico Zazzetti, Chetan S Karyekar, Graciela S Alarcón, Risto Alfredo Perich-Campos
Original research: Clinical and histopathological features of myositis in systemic lupus erythematosus (29 March, 2022)
Eleni Tiniakou, Daniel Goldman, Andrea Corse, Andrew Mammen, Michelle A Petri
Original research: Flare rates and factors determining flare occurrence in patients with systemic lupus erythematosus who achieved low disease activity or remission: results from a prospective cohort study (3 March, 2022)
Yanjie Hao, Lanlan Ji, Dai Gao, Yong Fan, Yan Geng, Xiaohui Zhang, Guangtao Li, Zhuoli Zhang
Original research: Assessing the validity of QRISK3 in predicting cardiovascular events in systemic lupus erythematosus (22 February, 2022)
Lisa Zhu, Manpreet Singh, Sonia Lele, Lori Sahakian, Jennifer Grossman, Bevra Hahn, Maureen McMahon
Original research: Cross-sectional study of the effects of self-efficacy on fatigue and pain interference in black women with systemic lupus erythematosus: the role of depression, age and education (11 February, 2022)
Cristina Drenkard, Kirk Easley, Gaobin Bao, Charmayne Dunlop-Thomas, S Sam Lim, Teresa Brady
Original research: Herpes zoster in SLE: prevalence, incidence and risk factors (11 January, 2022)
Andrew Kwan, Hanan Al Rayes, Tijana Lazova, Nicole Anderson, Dennisse Bonilla, Jiandong Su, Zahi Touma
Original research: Risk factors of flare in patients with systemic lupus erythematosus after glucocorticoids withdrawal. A systematic review and meta-analysis (7 January, 2022)
Lanlan Ji, Wenhui Xie, Serena Fasano, Zhuoli Zhang

Genetics

Original research:
Ancestry, ACKR1 and leucopenia in patients with systemic lupus erythematosus
(14 November, 2022)
Cecilia P Chung, Gul Karakoc, Ge Liu, Jorge L Gamboa, Jonathan D Mosley, Nancy J Cox, C Michael Stein, Vivian Kawai
Original research: Study of common hypertriglyceridaemia genetic variants and subclinical atherosclerosis in a group of women with SLE and a control group (23 August, 2022)
Marta Fanlo-Maresma, Virginia Esteve-Luque, Xavier Pintó, Ariadna Padró-Miquel, Emili Corbella, Beatriz Candás-Estébanez
Original research: Human leucocyte antigens profiling in Malay female patients with systemic lupus erythematosus: are we the same or different? (1 February, 2022)
Malarvili Selvaraja, Chun Lai Too, Lay Kim Tan, Bee Tee Koay, Maha Abdullah, Anim Md Shah, Masita Arip, Syafinaz Amin-Nordin

Immunology and inflammation

Original research: Intermuscular adipose tissue in patients with systemic lupus erythematosus (22 November, 2022)
Jorge Luis Gamboa, Daniel Carranza-León, Rachelle Crescenzi, Michael Pridmore, Dungeng Peng, Adriana Marton, Annette Oeser, Cecilia P Chung, Jens Titze, Charles Michael Stein, Michelle Ormseth
Original research: Comparison of short interval and low dose (SILD) with high dose of cyclophosphamide in the susceptibility to infection in SLE: a multicentrereal-world study (8 November, 2022)
Miao Shao, Miao Miao, Xia Zhang, Xiaoying Zhang, Yuan An, Huifang Guo, Lingyan Lei, Qing Zhao, Yanjie Ding, Jin Lin, Rui Wu, Feng Yu, Yucui Li, Huali Miao, Liyun Zhang, Yan Du, Ruiying Jiao, Lixia Pang, Li Long, Xueming Yao, Xiaofei Shi, Fei Wang, Luping Cui, Lei Zhang, Shengyun Liu, Fuai Lu, Kangkai Luo, Simeng Zhao, Yongfu Wang, Xiao Wu, Qingwen Wang, Hongjiang Liu, Shulin Song, Xiaoyuan Zhou, Xiaoping Zhang, Shumei Shi, Hong Zhu, Yao Chen, Honglian Yu, Jie Wu, Ruiyun Yu, Wenqiang Fan, Shuang Liu, Jian Xu, Zhibin Chen, Lianjie Shi, Jing He, Xuewu Zhang, Zhanguo Li, Ru Li
Original research:
CD4⁺ T-cell cooperation promoted pathogenic function of activated naïve B cells of patients with SLE
(30 September, 2022)
Kittikorn Wangriatisak, Piyawan Kochayoo, Pongsakorn Thawornpan, Chaniya Leepiyasakulchai, Thanitta Suangtamai, Pintip Ngamjanyaporn, Ladawan Khowawisetsut, Prasong Khaenam, Prapaporn Pisitkun, Patchanee Chootong
Original research: Role of autoantibodies and blood–brain barrier leakage in cognitive impairment in systemic lupus erythematosus (15 June, 2022)
John G Hanly, Alexandra Legge, Lyna Kamintsky, Alon Friedman, Javeria A Hashmi, Steven D Beyea, John Fisk, Antonina Omisade, Cynthia Calkin, Tim Bardouille, Chris Bowen, Kara Matheson, Marvin J Fritzler
Original research: Association between systemic lupus erythematosus and disruption of gut microbiota: a meta-analysis (28 March, 2022)
Shate Xiang, Yiqian Qu, Suhai Qian, Rongyun Wang, Yao Wang, Yibo Jin, Jie Li, Xinghong Ding
Original research: Iberdomide in patients with systemic lupus erythematosus: a randomised, double-blind, placebo-controlled, ascending-dose, phase 2a study (15 February, 2022)
Richard A Furie, Douglas R Hough, Allison Gaudy, Ying Ye, Shimon Korish, Nikolay Delev, Michael Weiswasser, Xiaojiang Zhan, Peter H Schafer, Victoria P Werth
Original research: Reductions in circulating B cell subsets and immunoglobulin G levels with long-term belimumab treatment in patients with SLE (7 February, 2022)
Herbert Struemper, Milena Kurtinecz, Lisa Edwards, William W Freimuth, David A Roth, William Stohl

Letter

Comparing dermatologic patient-reported outcome measures in cutaneous lupus erythematosus (15 December, 2022)
Grant Sprow, Joshua Dan, Rui Feng, Victoria P Werth
Are patients with systemic lupus erythematosus at increased risk for COVID-19? A bi-directional Mendelian randomisation study (24 August, 2022)
Shu Ran, Lixin Pan, Baolin Liu
Scleroderma-like capillaroscopic pattern in SLE is not a sign of overlap syndrome in both adults and children (18 July, 2022)
Sevdalina Nikolova Lambova
Activation-induced colocalisation of SCAMP5 with IFNα in human plasmacytoid dendritic cells (16 March, 2022)
Juliëtte N Pouw, Michel A M Olde Nordkamp, Tom G O'Toole, Timothy R D J Radstake, Emmerik F A Leijten, Marianne Boes
To treat or not to treat with immunosuppressive therapy: psychiatric disorders in patients with systemic lupus erythematosus (7 January, 2022)
Rory C Monahan, Anne M E Blonk, Tom WJ Huizinga, Margreet Kloppenburg, Huub A M Middelkoop, Nic J A van der Wee, Gerda M Steup-Beekman

Lupus nephritis

Original research: Response to therapy at 6 months predicts long-term renal outcome in lupus nephritis with poor kidney function (29 December, 2022)
Huiting Luo, Yangzhong Zhou, Gang Chen, Qidong Ren, Jiuliang Zhao, Wenling Ye, Yan Qin, Xuemei Li
Original research:
Molecular signatures of intrarenal complement receptors C3AR1 and C5AR1 correlate with renal outcome in human lupus nephritis
(15 December, 2022)
Désirée Tampe, Samy Hakroush, Björn Tampe
Original research: Mer-tyrosine kinase: a novel susceptibility gene for SLE related end-stage renal disease (4 November, 2022)
Sule Yavuz, Pascal Pucholt, Johanna K Sandling, Matteo Bianchi, Dag Leonard, Karin Bolin, Juliana Imgenberg-Kreuz, Maija-Leena Eloranta, Sergey V Kozyrev, Cristina M Lanata, Andreas Jönsen, Anders A Bengtsson, Christopher Sjöwall, Elisabet Svenungsson, Iva Gunnarsson, Solbritt Rantapää-Dahlqvist, ImmunoArray Development Consortium, DISSECT Consortium, Joanne Nititham, Lindsey A Criswell, Kerstin Lindblad-Toh, Lars Rönnblom
Original research: Interleukin (IL) 16: a candidate urinary biomarker for proliferative lupus nephritis (14 September, 2022)
Aliisa Häyry, Francesca Faustini, Agneta Zickert, Anders Larsson, Timothy B Niewold, Elisabet Svenungsson, Vilija Oke, Iva Gunnarsson
MOONLIGHT study: the design of a comparative study of the effectiveness of belimumab in patients with a history of lupus nephritis from the post-Marketed effectiveness of belimumab cOhOrt and JapaN Lupus NatIonwide reGistry (LUNA) coHorT (1 September, 2022)
Kenei Sada, Noriaki Kurita, Hisashi Noma, Taizo Matsuki, Holly Quasny, Roger A Levy, Angela R Jones-Leone, Kerry Gairy, Nobuyuki Yajima
Original research: Renal response at 2 years post biopsy to predict long-term renal survival in lupus nephritis: a retrospective analysis of the Hopkins Lupus Cohort (29 August, 2022)
Selin Cooper Blenkinsopp, Qinggong Fu, Yulia Green, Anuradha Madan, Patricia Juliao, Daniel W Goldman, David A Roth, Michelle A Petri
Original research: Predictors of increase in chronicity index and of kidney function impairment at repeat biopsy in lupus nephritis (16 August, 2022)
Gabriella Moroni, Giulia Porata, Francesca Raffiotta, Giulia Frontini, Marta Calatroni, Francesco Reggiani, Giovanni Banfi, Claudio Ponticelli
Original research: Urinary HER2, TWEAK and VCAM-1 levels are associated with new-onset proteinuria in paediatric lupus nephritis (2 August, 2022)
Patricia Costa-Reis, Kelly Maurer, Michelle A Petri, Daniella Levy Erez, Xue Zhao, Walter Faig, Jon Burnham, Kathleen O'Neil, Marisa S Klein-Gitelman, Emily von Scheven, Laura Eve Schanberg, Kathleen E Sullivan
Original research:
Characteristics and renal survival of patients with lupus nephritis with glomerular immunoglobulin G₄ deposition: a single-centre retrospective analysis
(16 June, 2022)
Xue Jiang, Lan Lan, Qin Zhou, Huijing Wang, Huiping Wang, Jianghua Chen, Fei Han
Original research: Clinical and histological findings at second but not at first kidney biopsy predict end-stage kidney disease in a large multicentric cohort of patients with active lupus nephritis (13 May, 2022)
Mariele Gatto, Francesca Radice, Francesca Saccon, Marta Calatroni, Giulia Frontini, Barbara Trezzi, Margherita Zen, Anna Ghirardello, Francesco Tamborini, Valentina Binda, Vincenzo L'Imperio, Andrea Doria, Augusto Vaglio, Renato Alberto Sinico, Gabriella Moroni, Luca Iaccarino
Original research: One-third of patients with lupus nephritis classified as complete responders continue to accrue progressive renal damage despite resolution of proteinuria (5 May, 2022)
Emma Weeding, Andrea Fava, Laurence Magder, Daniel Goldman, Michelle Petri
Original research: Metformin improves renal injury of MRL/lpr lupus-prone mice via the AMPK/STAT3 pathway (12 April, 2022)
Xiao-cui Chen, Dan Wu, Hong-luan Wu, Hui-yuan Li, Chen Yang, Hong-yong Su, Ze-jian Liu, Xiao-rong Huang, Xing Lu, Li-feng Huang, Shao-ping Zhu, Qing-jun Pan, Ning An, Hua-feng Liu
Original research: Immune gene expression and functional networks in distinct lupus nephritis classes (24 January, 2022)
Alyssa C Gilmore, Hannah R Wilson, Thomas D Cairns, Marina Botto, Liz Lightstone, Ian N Bruce, Herbert Terence Cook, Matthew Caleb Pickering
Original research: Membrane attack complex (MAC) deposition in renal tubules is associated with interstitial fibrosis and tubular atrophy: a pilot study (7 January, 2022)
Shudan Wang, Ming Wu, Luis Chiriboga, Briana Zeck, Beatrice Goilav, Shuwei Wang, Alejandra Londono Jimenez, Chaim Putterman, Daniel Schwartz, James Pullman, Anna Broder, H Michael Belmont

Protocol

Low-dose belimumab for patients with systemic lupus erythematosus at low disease activity: protocol for a multicentre, randomised, double-blind, placebo-controlled clinical trial (1 February, 2022)
Fangfang Sun, Wenyan Huang, Jie Chen, Liling Zhao, Danting Zhang, Xiaodong Wang, Weiguo Wan, Sheng-Ming Dai, Sheng Chen, Ting Li, Shuang Ye

Reproductive health and APS

Original research: Pregnancy outcomes in antiphospholipid antibody positive patients: prospective results from the AntiPhospholipid Syndrome Alliance for Clinical Trials and InternatiOnal Networking (APS ACTION) Clinical Database and Repository (‘Registry’) (14 June, 2022)
Zeynep Belce Erton, Ecem Sevim, Guilherme Ramires de Jesús, Ricard Cervera, Lanlan Ji, Vittorio Pengo, Amaia Ugarte, Danieli Andrade, Laura Andreoli, Tatsuya Atsumi, Paul R Fortin, Maria Gerosa, Yu Zuo, Michelle Petri, Savino Sciascia, Maria G Tektonidou, Maria Angeles Aguirre- Zamorano, D Ware Branch, Doruk Erkan
Original research: Hydroxychloroquine in the pregnancies of women with lupus: a meta-analysis of individual participant data (21 March, 2022)
Megan E B Clowse, Amanda M Eudy, Stephen Balevic, Gillian Sanders-Schmidler, Andrzej Kosinski, Rebecca Fischer-Betz, Dafna D Gladman, Yair Molad, Cecilia Nalli, Abir Mokbel, Angela Tincani, Murray Urowitz, Caroline Bay, Megan van Noord, Michelle Petri
Original research: Impact of pregnancy in patients with systemic lupus erythematosus-associated pulmonary arterial hypertension: case series and literature review (7 March, 2022)
Mucong Li, Zhuang Tian, Junyan Qian, Can Huang, Jiuliang Zhao, Qian Wang, Yijun Song, Xinping Tian, Mengtao Li, Juntao Liu, Xiaofeng Zeng
Original research: Hydroxychloroquine PK and exposure-response in pregnancies with lupus: the importance of adherence for neonatal outcomes (7 January, 2022)
Stephen J Balevic, Daniel Weiner, Megan E B Clowse, Amanda M Eudy, Anil R Maharaj, Christoph P Hornik, Michael Cohen-Wolkowiez, Daniel Gonzalez

Review

Infertility in systemic lupus erythematosus: what rheumatologists need to know in a new age of assisted reproductive technology (13 December, 2022)
Bessie Stamm, Medha Barbhaiya, Caroline Siegel, Sarah Lieber, Michael Lockshin, Lisa Sammaritano
Conceptual framework for defining disease modification in systemic lupus erythematosus: a call for formal criteria (28 March, 2022)
Ronald van Vollenhoven, Anca D Askanase, Andrew S Bomback, Ian N Bruce, Angela Carroll, Maria Dall'Era, Mark Daniels, Roger A Levy, Andreas Schwarting, Holly A Quasny, Murray B Urowitz, Ming-Hui Zhao, Richard Furie
Central nervous system infections in patients with systemic lupus erythematosus: a systematic review and meta-analysis (3 January, 2022)
Kasra Molooghi, Fereshte Sheybani, Hamidreza Naderi, Zahra Mirfeizi, Negar Morovatdar, Ashkan Baradaran

Correction

Correction: 2021 DORIS definition of remission in SLE: final recommendations from an international task force (7 February, 2022)

Main menu

Table of contents

2022 - Volume 9 - 1

Animal models

Brief communication

Biomarker studies

Childhood lupus

Clinical trials and drug discovery

Co-morbidities

Cutaneous lupus

Dialogue

Epidemiology and outcomes

Genetics

Immunology and inflammation

Letter

Lupus nephritis

Protocol

Reproductive health and APS

Review

Correction

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Table of contents

2022 - Volume 9 - 1

Animal models

Brief communication

Biomarker studies

Childhood lupus

Clinical trials and drug discovery

Co-morbidities

Cutaneous lupus

Dialogue

Epidemiology and outcomes

Genetics

Immunology and inflammation

Letter

Lupus nephritis

Protocol

Reproductive health and APS

Review

Correction