Lupus Science & Medicine: 11 (1)

Biomarker studies

Original research: Novel potential lncRNA biomarker in B cells indicates essential pathogenic pathway activation in patients with SLE (10 April, 2024)
Xinyi Zhu, Yashuo Chen, Zhihua Yin, Yutong Zhang, Yiwei Shen, Dai Dai, Xiaojing Lin, Ling-Hua Zou, Nan Shen, Zhizhong Ye, Huihua Ding, Guojun Hou
Original research: Anti-KIF20B autoantibodies are associated with cranial neuropathy in systemic lupus erythematosus (9 April, 2024)
Eugene Krustev, John G Hanly, Ricky Chin, Katherine A Buhler, Murray B Urowitz, Caroline Gordon, Sang-Cheol Bae, Juanita Romero-Diaz, Jorge Sánchez-Guerrero, Sasha Bernatsky, Daniel J Wallace, David Isenberg, Anisur Rahman, Joan T Merrill, Paul R Fortin, Dafna D Gladman, Ian N Bruce, Michelle A Petri, Ellen M Ginzler, Mary Anne Dooley, Rosalind Ramsey-Goldman, Susan Manzi, Andreas Jönsen, Graciela S Alarcón, Ronald F van Vollenhoven, Cynthia Aranow, Meggan Mackay, Guillermo Ruiz-Irastorza, Sam Lim, Murat Inanc, Kenneth C Kalunian, Søren Jacobsen, Christine A Peschken, Diane L Kamen, Anca Askenase, Jill Buyon, Marvin J Fritzler, Ann E Clarke, May Y Choi
Original research:
Potential involvement of circulating exosomal miRNA-146a in disease activity and TRAF6 gene expression in juvenile proliferative lupus nephritis
(14 February, 2024)
Poorichaya Somparn, Aunaymon Srichaimongkol, Suwaphit Jungjing, Bunsita Wanthong, Saharat Nanthawong, Leelahavanichkul Asada, Marut Tangwattanachuleepron, Pornpimol Rianthavorn
Original research: Novel multiclass classification machine learning approach for the early-stage classification of systemic autoimmune rheumatic diseases (31 January, 2024)
Yun Wang, Wei Wei, Renren Ouyang, Rujia Chen, Ting Wang, Xu Yuan, Feng Wang, Hongyan Hou, Shiji Wu

Childhood lupus

Original research: Rituximab as an effective add-on maintenance therapy for disease activities in childhood-onset systemic lupus erythematosus (19 January, 2024)
Ting-Wei Lin, Yu-Tsan Lin, Ya-Chiao Hu, Hsin-Hui Yu, Bor-Luen Chiang

Clinical trials and drug discovery

Original research: Mezagitamab in systemic lupus erythematosus: clinical and mechanistic findings of CD38 inhibition in an autoimmune disease (7 March, 2024)
Scott R P McDonnell, Van Anh Nguyen, Noah M Walton, Carsten Merkwirth, Feng Hong, Deborah Berg, Elena Tomaselli Muensterman, Richard A Furie
Original research: Evaluation of RNase therapy in systemic lupus erythematosus: a randomised phase 2a clinical trial of RSLV-132 (7 February, 2024)
Daniel J Burge, Victoria P Werth, Susan A Boackle, James Posada
Original research: Fragility of randomised controlled trials for systemic lupus erythematosus and lupus nephritis therapies (10 January, 2024)
Gabriel Figueroa-Parra, Michael S Putman, Cynthia S Crowson, Alí Duarte-García

Co-morbidities

Original research: Higher mortality risk from gynaecological neoplasms and non-Hodgkin’s lymphoma in patients with systemic lupus erythematosus: an observational study from the Spanish National Registry (17 April, 2024)
Víctor Moreno-Torres, María Martínez-Urbistondo, José Vázquez-Comendador, María Mateos Seirul-lo, Raquel Castejón, Ana Huerta, Pedro Durán-del Campo, Pablo Tutor, Susana Mellor-Pita
Original research: SLESIS-R: an improved score for prediction of serious infection in patients with systemic lupus erythematosus based on the RELESSER prospective cohort (8 April, 2024)
Iñigo Rua-Figueroa, M Jesus García de Yébenes, Julia Martinez-Barrio, Maria Galindo Izquierdo, Jaime Calvo Alén, Antonio Fernandez-Nebro, Raúl Menor-Almagro, Loreto Carmona, Beatriz Tejera Segura, Eva Tomero, Mercedes Freire-González, Clara Sangüesa, Loreto Horcada, Ricardo Blanco, Esther Uriarte Itzazelaia, Javier Narváez, José Carlos Rosas Gómez de Salazar, Silvia Gómez-Sabater, Claudia Moriano Morales, Jose L Andreu, Vicente Torrente Segarra, Elena Aurrecoechea, Ana Perez, Javier Nóvoa Medina, Eva Salgado, Nuria Lozano-Rivas, Carlos Montilla, Esther Ruiz-Lucea, Marta Arevalo, Carlota Iñiguez, María Jesús García-Villanueva, Lorena Exposito, Mónica Ibáñez-Barceló, Gema Bonilla, Irene Carrión-Barberà, Celia Erausquin, Jorge Juan Fragio Gil, Angela Pecondón, Francisco J Toyos, Tatiana Cobo, Alejandro Muñoz-Jiménez, Jose Oller, Joan M Nolla, J M Pego-Reigosa
Original research: High-density lipoprotein cholesterol subfraction HDL2 is associated with improved endothelial function in systemic lupus erythematosus (22 January, 2024)
Ainsley Ryan Yan Bin Lee, Chun En Yau, Cheryl Kai Ting Chua, Wan Ling Cheng, Avery Joy Li Chia, Shi Yin Wong, Nien Yee Kow, Lingli Gong, Bernett Teck Kwong Lee, Lieng Hsi Ling, Anselm Mak, Tze Ping Loh, Sen Hee Tay

Epidemiology and outcomes

Original research: Comparison of cognitive performance measures in individuals with systemic lupus erythematosus (16 April, 2024)
Laura Plantinga, Jinoos Yazdany, C Barrett Bowling, Charmayne Dunlop-Thomas, Courtney Hoge, Brad D Pearce, S Sam Lim, Patricia Katz
Original research: Evaluating the real-world effectiveness of belimumab in patients with SLE using SLE-related laboratory values and rheumatoid arthritis-derived disease activity measures: RAPID3, swollen joint count and tender joint count (3 April, 2024)
Guillaume Germain, Karen Worley, Sean D MacKnight, Bernard Rubin, Christopher F Bell, François Laliberté, Ana Urosevic, Mei Sheng Duh, Andrew Concoff
Prevalence of coeliac disease in patients with systemic lupus erythematosus: a systematic review and meta-analysis (13 February, 2024)
Adonis Sotoodeh, Madeleine Nguyen Hoang, Karin Hellgren, Anders Forss
Original research: Joint surgery rates in lupus: a long-term cohort study (10 January, 2024)
Johannes Nossent, Helen Isobel Keen, David Brian Preen, Charles A Inderjeeth

Genetics

Association of genetic variation on X chromosome with systemic lupus erythematosus in both Thai and Chinese populations (8 March, 2024)
Pattarin Tangtanatakul, Yao Lei, Krisana Jaiwan, Wanling Yang, Manon Boonbangyang, Punna Kunhapan, Pimpayao Sodsai, Surakameth Mahasirimongkol, Prapaporn Pisitkun, Yi Yang, Jakris Eu-Ahsunthornwattana, Wichai Aekplakorn, Natini Jinawath, Nareemarn Neelapaichit, Nattiya Hirankarn, Yong-Fei Wang

Immunology and inflammation

Original research: Enhanced medullary and extramedullary granulopoiesis sustain the inflammatory response in lupus nephritis (11 March, 2024)
Eleni Zervopoulou, Maria Grigoriou, Stavros A Doumas, Danae Yiannakou, Pavlos Pavlidis, Gilles Gasparoni, Jörn Walter, Anastasia Filia, Harikleia Gakiopoulou, Aggelos Banos, Ioannis Mitroulis, Dimitrios T Boumpas
Original research: Celastrol ameliorates lupus by promoting apoptosis of autoimmune T cells and preventing autoimmune response in MRL/lpr mice (11 March, 2024)
Tianhong Xie, Hongliang Rui, Huiqiang Liu, Xin Liu, Xiang Liu, Ping Li
Original research: Add-on sirolimus for the treatment of mild or moderate systemic lupus erythematosus via T lymphocyte subsets balance (13 February, 2024)
Meng Ding, Lu Jin, Jinwen Zhao, Lin Yang, Shaoxin Cui, Xiaoping Wang, Jingjing He, Fei Chang, Min Shi, Jun Ma, Shuran Song, Hongtao Jin, Aijing Liu

Letter

Enhancing lupus outcomes by means of biology beyond overt clinical features, exemplified in an in-depth investigation of the effects of circadian rhythm disruption (9 April, 2024)
Ioannis Parodis
Concentrations of subcutaneously administered belimumab in human breast milk of a woman with systemic lupus erythematosus: a case report (18 March, 2024)
Birgit S Blomjous, Marjon A de Boer, Mirjam M van Weissenbruch, Koen C J Laan, Theo Rispens, Alexandre E Voskuyl, Irene E M Bultink
Expert consensus achieved on a working core outcome set for cutaneous lupus erythematosus research in survey following the 5th International Conference on Cutaneous Lupus Erythematosus (ICCLE) (26 February, 2024)
Arianna J Zhang, Lourdes M Perez-Chada, Victoria P Werth, Joseph F Merola

Lupus nephritis

Original research: Machine learning-based identification of novel hub genes associated with oxidative stress in lupus nephritis: implications for diagnosis and therapeutic targets (18 April, 2024)
Huiqiong Zeng, Yu Zhuang, Xiaodong Yan, Xiaoyan He, Qianwen Qiu, Wei Liu, Ye Zhang
Original research: Exacerbating effects of circadian rhythm disruption on the systemic lupus erythematosus (9 April, 2024)
Luping Shen, Mo Han, Xuan Luo, Qixiang Zhang, Huanke Xu, Jing Wang, Ning Wei, Qing Liu, Guangji Wang, Fang Zhou
Therapeutic drug monitoring of mycophenolic acid and clinical outcomes of lupus nephritis: a systematic review and meta-analysis (17 January, 2024)
Thunyatorn Wuttiputhanun, Nuanjanthip Naiyarakseree, Suwasin Udomkarnjananun, Wonngarm Kittanamongkolchai, Leelahavanichkul Asada, Pajaree Chariyavilaskul, Natavudh Townamchai, Yingyos Avihingsanon
Original research: Circulating neutrophil extracellular trap remnants as a biomarker to predict outcomes in lupus nephritis (4 January, 2024)
Laura Patricia Whittall-Garcia, Farnoosh Naderinabi, Dafna D Gladman, Murray Urowitz, Zahi Touma, Ana Konvalinka, Joan Wither

Reproductive health and APS

Original research: Differences in reproductive health discussions in an urban Hispanic population with SLE: lessons from the field (20 February, 2024)
Martha Delgado, Jack Rodman, Meredith Xepoleas, Michael Weisman, Leanna Marderian Wise
Original research: Risk factors of first thrombosis in obstetric antiphospholipid syndrome (3 January, 2024)
Liang Luo, Qingmeng Cai, Xiangjun Liu, Yuke Hou, Chun Li
Original research: Azathioprine metabolite levels and outcomes during pregnancies with rheumatic disease (3 January, 2024)
Stephen Balevic, Catherine A Sims, Amanda Eudy, Valerie Smith, Megan Clowse

Review

Systemic lupus in the era of machine learning medicine (4 March, 2024)
Kevin Zhan, Katherine A Buhler, Irene Y Chen, Marvin J Fritzler, May Y Choi
Clinical trial outcomes for SLE: what we have and what we need (15 February, 2024)
Laurent Arnaud, Ioannis Parodis, Hervé Devilliers, Francois Chasset

Short report

Association of phenotypic frailty and hand grip strength with telomere length in SLE (22 March, 2024)
Sarah B Lieber, Robyn A Lipschultz, Shahrez Syed, Mangala Rajan, Sara Venkatraman, Myriam Lin, M Carrington Reid, Neal F Lue, Lisa A Mandl
Large overlap in neutrophil transcriptome between lupus and COVID-19 with limited lupus-specific gene expression (31 January, 2024)
Rayan Najjar, Noga Rogel, Jose Mario Bello Pineda, Xiaoxing Wang, Megan Tran, Alison Bays, Tomas Mustelin

Systematic review

Cardiovascular risk factors and complications in patients with systemic lupus erythematosus with and without nephritis: a systematic review and meta-analysis (21 March, 2024)
Cheuk Yin Wong, Becky M Y Ma, Danting Zhang, Wynn Cheung, Tak Mao Chan, Desmond Y H Yap

Correction

Correction: Cervus and cucumis peptides ameliorates bone erosion in experimental arthritis by inhibiting osteoclastogenesis (19 January, 2024)

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Current Issue

2024 - Volume 11 - 1

Biomarker studies

Childhood lupus

Clinical trials and drug discovery

Co-morbidities

Epidemiology and outcomes

Genetics

Immunology and inflammation

Letter

Lupus nephritis

Reproductive health and APS

Review

Short report

Systematic review

Correction

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Current Issue

2024 - Volume 11 - 1

Biomarker studies

Childhood lupus

Clinical trials and drug discovery

Co-morbidities

Epidemiology and outcomes

Genetics

Immunology and inflammation

Letter

Lupus nephritis

Reproductive health and APS

Review

Short report

Systematic review

Correction