Clinical diagnoses formulated by the examining rheumatologists in the participating centre
| Nested cohort—547 patients | 37 dropout patients | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Diagnoses | ANA pos (N=288) | ANA neg (N=259) | Rate ratio* | Total | Total | ||||
| N | Per cent | n | Per cent | n | Per cent | n | Per cent | ||
| Systemic lupus erythematosus | 57 | 19.8 | 6 | 2.3 | 8.61 | 63 | 11.5 | 2 | 5.4 |
| Inflammatory connective tissue disease | 44 | 15.3 | 12 | 4.6 | 3.33 | 56 | 10.2 | 0 | 0 |
| Inflammatory joint disease | 49 | 17 | 95 | 36.7 | 0.46 | 144 | 26.3 | 13 | 35.1 |
| Systemic inflammatory disease | 10 | 3.5 | 17 | 6.6 | 0.53 | 27 | 4.9 | 2 | 5.4 |
| Arthralgia | 45 | 15.6 | 32 | 12.35 | 1.26 | 77 | 14.1 | 6 | 16.2 |
| Osteoarthritis | 25 | 8.7 | 29 | 11.2 | 0.78 | 54 | 10 | 5 | 13.5 |
| Soft-tissue rheumatism | 8 | 2.8 | 25 | 9.65 | 0.29 | 33 | 6.0 | 3 | 8.1 |
| Non-rheumatic disease | 34 | 11.8 | 26 | 10 | 1.18 | 60 | 11 | 3 | 8.1 |
| Dermatological disorder | 10 | 3.5 | 7 | 2.7 | 1.30 | 16 | 2.9 | 2 | 5.4 |
| Unspecified | 7 | 2.4 | 10 | 3.9 | 0.61 | 17 | 3.1 | 1 | 2.7 |
*Ratio between prevalence of manifestation in ANA positive and ANA negative patients.
ANA, antinuclear antibodies.