Proposed criteria for use of second-line therapy in refractory systemic lupus erythematosus-associated haemolytic anaemia43
| Basis of criteria | Comment | |
|---|---|---|
| Time based | No response to glucocorticoid in 3 weeks | Second-line therapy required |
| Dose based | >15 mg/day of prednisone* for maintenance | Second-line therapy required |
| 15 mg/day to 0.1 mg/kg/day* | Second-line therapy encouraged | |
| <0.1 mg/kg/day | No second-line therapy |
*Or the equivalent of 15 mg of prednisone.