Association between maternal antiphospholipid antibody syndrome (APS) and special educational (SE) services requirement among offspring
| Covariates | Any SE service (n=15) | SE service age ≥2 years (n=14) |
|---|---|---|
| OR (95% CI) | OR (95% CI) | |
| APS (crude) | 5.1 (1.2 to 22.6)* | 7.8 (1.6 to 38.6)* |
| APS adjusted for: | ||
| +Pregnancy duration (weeks) | 4.1 (0.9 to 19.3) | 6.7 (1.3 to 35.2)* |
| +Small for gestational age | 5.0 (1.1 to 22.3)* | 7.6 (1.5 to 38.3)* |
| +Maternal education (years) | 4.3 (0.9 to 19.8) | 7.5 (1.4 to 39.1)* |
| +Lupus anticoagulant | 3.8 (0.8 to 18.1) | 5.5 (1.1 to 28.7)* |
| +Heparin | 4.0 (0.9 to 18.5) | 6.8 (1.3 to 35.1)* |
| +Pscore +AZA | 4.2 (0.82 to 21.7) | 9.4 (1.47 to 60.0)* |
| Lupus anticoagulant (crude) | 4.0 (1.1 to 14.7)* | 3.2 (0.9 to 12.1) |
| +APS | 3.6 (0.9 to 13.8) | 2.6 (0.7 to 10.5) |
ORs represent the effect estimates for APS based on the crude (univariate) logistic regression models and additional bivariate logistic regression models adjusted for the covariates listed.
*Indicates statistical significance (p<0.05).
APS, antiphospholipid antibody syndrome; DD, developmental delay.