Laboratory findings at the time for repeat biopsy and clinical response in patients with baseline PN in histopathological responders vs non-responders
| HR (n=27) | HNR (n=30) | p Value | |
|---|---|---|---|
| Creatinine, µmol/L | 74 (48–306) | 76 (45–122) | 0.88 |
| Albuminuria, g/day | 0.2 (0–3.4) | 0.6 (0.03–3.1) | 0.007 |
| Anti-DNA IU/mL* | 18 (<5–250) | 49 (<5–300) | 0.03 |
| C3, g/L | 0.74 (0.4–1.38) | 0.81 (0.38–1.51) | 0.83 |
| C4, g/L | 0.13 (0.04–0.3) | 0.13 (0.03–0.45) | 0.53 |
| Hematuria†, % | 30 | 54 | 0.11 |
| Clinical response, n | |||
| CR | 12 | 5 | |
| PR | 7 | 8 | |
| NR | 8 | 17 |
All statistical significant p-values (p<0.05) are in italics. Values are presented as median (range) unless otherwise indicated.
*Available in 47 patients.
†u-erytrocytes >1+ in % of patients.
C3, complement component 3; C4, complement component 4; CR, complete response; HNR, histopathological non-response; HR, histopathological response; n, number of patients; NR, non-response; PN, proliferative nephritis; PR, partial response.