Standardised incidence ratios (SIRs) and 95% CIs in US non-systemic lupus erythematosus renal transplant recipients compared with the US general population stratified by race/ethnicity
| Cancer type | Observed cases* | Expected cases* | Overall SIR (95% CI) | White SIR (95% CI) | Non-white SIR (95% CI) | Hispanic SIR (95% CI) | Non-Hispanic SIR (95% CI) |
|---|---|---|---|---|---|---|---|
| All cancers | 1739 | 469 | 3.7 (2.4 to 5.7) | 4.0 (2.3 to 5.7) | 3.7 (2.3 to 5.2) | 4.8 (3.2 to 6.4) | 3.9 (2.3 to 5.5) |
| Lip/oropharyngeal | 665 | 11 | 60.4 (36.2 to 80.1) | 47.9 (26.5 to 69.2) | 59.5 (30.5 to 88.6) | 91.1 (42.8 to 139.4) | 48.0 (25.8 to 70.1) |
| Kaposi | 42 | 1 | 42 (55.2 to 89.9) | 67.2 (54.8 to 79.5) | 49.4 (24.6 to 64.2) | 62.0 (26.1 to 97.9) | 91.0 (71.4 to 110.5) |
| Neuroendocrine† | 74 | 5 | 14.8 (11.3 to 58.2) | 11.8 (2.6 to 21.1) | 12.9 (2.4 to 23.5) | 12.0 (1.6 to 22.4) | 15.0 (2.4 to 25.5) |
| Thyroid | 238 | 10 | 23.8 (14.6 to 38.5) | 21.3 (16.9 to 25.7) | 42.4 (36.9 to 48.0) | 30.4 (23.6 to 37.3) | 21.8 (16.8 to 26.7) |
| Renal | 142 | 14 | 10.1 (7.6 to 12.6) | 7.7 (5.7 to 9.7) | 13.5 (10.1 to 16.9) | 9.5 (6.7 to 12.3) | 9.9 (7.4 to 12.4) |
| Cervical | 144 | 9 | 16.7 (11.7 to 21.6) | 16.1 (11.1 to 21.0) | 13.2 (10.4 to 16.0) | 11.8 (7.5 to 16.1) | 19.8 (13.5 to 21.0) |
| Lymphoma | 194 | 22 | 9.0 (7.4 to 10.5) | 8.2 (6.7 to 98) | 12.5 (10.1 to 15.0) | 12.8 (9.2 to 16.4) | 8.1 (6.6 to 9.6) |
| Liver | 17 | 7 | 9.0 (7.4 to 10.5) | 2.5 (1.6 to 3.5) | 2.6 (1.5 to 3.7) | 2.6 (2.0 to 3.3) | 3.1 (2.0 to 4.3) |
| Colorectal | 150 | 50 | 2.8 (2.2 to 3.4) | 3.2 (2.2 to 4.3) | 2.5 (1.6 to 3.5) | 3.7 (2.5 to 4.9) | 2.8 (2.2 to 3.4) |
| Ovarian | 17 | 13 | 1.3 (0.7 to 1.8) | 1.0 (0.5 to 1.5) | 1.4 (0.9 to 1.9) | 4.2 (2.0 to 6.3) | 1.0 (0.6 to 1.4) |
| Melanoma | 22 | 20 | 1.0 (0.7 to 1.3) | 1.0 (0.7 to 1.3) | 15.2 (6.9 to 23.5) | 5.0 (1.1 to 8.9) | 0.9 (0.6 to 1.1) |
| Breast | 280 | 127 | 2.1 (1.3 to 2.8) | 1.6 (0.9 to 2.3) | 2.4 (1.3 to 3.5) | 2.6 (1.4 to 3.9) | 1.7 (0.9 to 2.6) |
| Lung | 90 | 64 | 1.4 (1.0 to 1.7) | 1.4 (0.9 to 1.8) | 1.2 (0.8 to 1.5) | 1.3 (1.1 to 1.6) | 1.4 (1.0 to 1.8) |
| Prostate | 65 | 163 | 0.4 (0.2 to 0.5) | 0.3 (0.2 to 0.4) | 0.3 (0.2 to 0.4) | 0.4 (0.1 to 0.7) | 1.1 (0.2 to 2.0) |
*Observed and expected cases reported per 100 000 person-years.
†Neuroendocrine tumours included carcinoid, islet cell, medullary thyroid, Merkel cell and pheochromocytoma.