Relationship between venous thrombotic event and mean levels of anticardiolipin isotypes
| aCL measure | Subgroup defined by geometric mean titre over all measures during cohort | No. of thromboses | No. of person-years | Rate (per 1000) | Rate ratios* | p Value |
|---|---|---|---|---|---|---|
| IgG | <20 | 152 | 17 259 | 9.2 | 1.0 (Ref group) | |
| 20+ | 16 | 935 | 17.1 | 1.9 (1.1, 3.2) | 0.015 | |
| IgM | <20 | 157 | 17 315 | 9.1 | 1.0 (Ref group) | |
| 20+ | 11 | 879 | 12.5 | 1.3 (0.7, 2.4) | 0.36 | |
| IgA | <20 | 165 | 17 995 | 9.2 | 1.0 (Ref group) | |
| 20+ | 3 | 199 | 15.1 | 1.7 (0.5, 5.3) | 0.37 | |
| RVVT | <45 | 100 | 16 173 | 6.2 | 1.0 (Ref. group) | |
| 45+ | 13 | 1071 | 12.1 | 1.9 (1.1, 3.4) | 0.028 |
aCL, anticardiolipin antibody; RVVT, Russell's viper venom time.