Relationship between any thrombotic event and mean levels of anticardiolipin isotypes
| aCL measure | Subgroup defined by geometric mean titre over all measures during cohort | No. of thromboses | No. of person-years | Rate (per 1000) | Rate ratios | p Value |
|---|---|---|---|---|---|---|
| IgG | <20 (n=1318) | 259 | 16 175 | 16.1 | 1.0 (Ref. group) | |
| 20+ (n=72) | 25 | 850 | 29.4 | 1.8 (1.2, 2.7) | 0.0052 | |
| IgM | <20 (n=1320) | 267 | 16 219 | 16.5 | 1.0 (Ref. group) | |
| 20+ (n=70) | 17 | 809 | 21.0 | 1.2 (0.8, 2.0) | 0.40 | |
| IgA | <20 (n=1379) | 279 | 16 848 | 16.7 | 1.0 (Ref. group) | |
| 20+ (n=11) | 5 | 177 | 28.2 | 1.7 (0.7, 4.2) | 0.23 | |
| RVVT | <45 (n=1208) | 191 | 15 243 | 12.5 | 1.0 (Ref. group) | |
| 45+ (n=78) | 22 | 1015 | 21.7 | 1.7 (1.1, 2.6) | 0.021 |
aCL, anticardiolipin antibody; RVVT, Russell's viper venom time.