Traditional and SLE-related cardiovascular risk factors in different age groups
| Group 1 (≤34 years) | Group 2 (35–49 years) | Group 3 (≥50 years) | |
|---|---|---|---|
| HTN, n/N (%) | 4/37 (10.8) | 20/84 (23.8) | 47/95 (49.4) |
| DM, n/N (%) | 0/37 (0) | 3/84 (3.5) | 4/95 (4.2) |
| DLP, n/N (%) | 3/37 (8.1) | 20/84 (23.8) | 51/95 (53.6) |
| Current smoker, n/N (%) | 15/37 (40.5) | 28/84 (33.3) | 22/95 (23.1) |
| Smoker (ever), n/N (%) | 18/37 (48.6) | 49/84 (58.3) | 41/95 (43.1) |
| Family history, n/N (%) | 2/37 (5.4) | 10/84 (11.9) | 13/95 (13.6) |
| Abdominal obesity, n/N (%) | 10/37 (27) | 25/84 (29.7) | 38/95 (40) |
| BMI, n/N (%) overweight–obesity | 13/37 (35.1) | 44/84 (52.3) | 52/95 (54.7) |
| Sedentary lifestyle, n/N (%) | 20/37 (54) | 35/84 (41.6) | 42/95 (44.2) |
| Any vascular risk factor, n/N (%) | 22/37 (59.4) | 59/84 (70.2) | 80/95 (84.2) |
| MS, n/N (%) | 3/37 (8.1) | 6/84 (7.1) | 12/95 (12.6) |
| APS, n/N (%) | 2/37 (5.4) | 10/84 (11.9) | 9/95 (9.4) |
| aPL, n/N (%) | 14/37 (29.7) | 27/84 (32.1) | 33/95 (34.7) |
| Lupus nephritis, n/N (%) | 12/37 (32.4) | 30/84 (35.7) | 18/95 (18.9) |
| SLEDAI at dx, mean (SD) | 9.83 (7.8) | 8.15 (5.3) | 6.1 (3.9) |
| SLEDAI at ABI, mean (SD) | 3.08 (3.7) | 2.05 (2.9) | 1.5 (2.2) |
| SDI at ABI, mean (SD) | 0.4 (0.8) | 0.98 (1.2) | 1.5 (1.5) |
| Age at SLE dx, years, mean (SD) | 21.4 (6.1) | 30.2 (9.2) | 47.4 (15.6) |
| Disease duration, years, mean (SD) | 6.2 (5.3) | 11.7 (8.5) | 15 (10.5) |
Any vascular risk factor: DLP, hypercholesterolaemia; HTN, DM, dyslipidaemia or smoking exposed. ABI, ankle–brachial index; aPL, antiphospholipid antibodies (anticardiolipin and/or lupus anticoagulant); APS, antiphospholipid syndrome; BMI, body mass index; DM, diabetes mellitus; dx, diagnosis; HTN, arterial hypertension; MS, metabolic syndrome according to ATPIII.