Improvements of at least two BILAG grades seen in each of the eight organ/systems at 6 months post-BCD
| BILAG score | Constitutional | Mucocutaneous | Neurological | Musculoskeletal | Cardiorespiratory | Vasculitic | Renal | Haemological |
|---|---|---|---|---|---|---|---|---|
| Total BILAG A/B scores at baseline | 6 | 7 | 0 | 10 | 0 | 1 | 2 | 3 |
| Total change at 6 months post-BCDT | ||||||||
| A→B | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
| A→C | 1 | 2 | 0 | 0 | 0 | 0 | 0 | 0 |
| A→D | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
| B→C | 4 | 1 | 0 | 5 | 0 | 0 | 0 | 1 |
| B→D | 1 | 2 | 0 | 3 | 0 | 1 | 1 | 0 |
| BILAG scores A/B remaining unchanged post-BCDT | – | – | – | – | – | – | 1 | 2 |
BCD, B-cell depletion; BCDT, B-cell depletion treatment; BILAG, British Isles Lupus Assessment Group.