Table 1

The baseline data including organs/systems involved and the treatment given to those patients treated with BCD

Patient	Age of diagnosis	Follow-up (years)	Ethnicity	Symptom duration before diagnosis (weeks)	Clinical features and serology at SLE diagnosis	CYC post-BCDT	AZA post-BCDT	MMF post-BCDT	Additional RTX
1	36	5	Caucasian	5	Arthritis, fatigue, ANA, ↑ anti-dsDNA, lymphopenia, ↓ C3	Yes	Yes	No	No
2	31	7	Caucasian	384	Discoid lupus, malar rash, Raynaud's, alopecia, pleurisy, ↑ anti-dsDNA, lymphopenia	Yes	Yes	No	No
3	26	6	Malaysian/Chinese	16	Discoid lupus, alopecia, Raynaud's, arthralgia, ANA, anti-SM, lymphopenia	No	Yes	No	No
4	39	6	Caucasian	40	Arthritis, serosits, ANA, ↑ anti-dsDNA, lymphopenia, ↑aCL	Yes	Yes	No	No
5	47	7	African-Caribbean	12	Arthritis, rash, alopecia, ANA, lymphopenia	No	No	No	No
6	21	1	Chinese	4	Rash, fever, angiooedema, arthritis, ANA, ↑ anti-dsDNA, lymphopenia, ↓ C3	Yes	Yes	No	No
7	34	3	African-Caribbean	6	Arthritis, rash, alopecia, ANA, lymphopenia	Yes	No	No	Yes
8	47	6	African-Caribbean	6	Fever, fatigue, alopecia, rash, arthritis, serositis, ANA, anti-CCP	Yes	Yes	No	No
9	44	5	Caucasian	4	Livedo reticularis, serositis, rash, proteinuria, ANA, ↑ anti-dsDNA, lymphopenia, ↓ C3, ↑aCL and LA	Yes	Yes	No	No
10	29	5	African-Caribbean	6	Arthritis, rash, alopecia, ↑ anti-dsDNA, ↓ C3, ANA, RNP	Yes	Yes	yes	Yes
11	50	5	Caucasian	12	Raynaud's, ANA, Ro, arthritis, mouth ulcers, photosensitivity, rash, Sjögren's syndrome	Yes	Yes	No	Yes
12	26	1	Caucasian	20	Arthritis, ANA, p-ANCA, ↑ anti-dsDNA, anti-SM, RNP, ↓ C3	No	Yes	No	No
13	34	2	Caucasian	2	Arthritis, ANA, rash, Sjögren's syndrome, ↑ anti-dsDNA, ↓ C3, renal failure	Yes	No	yes	No
14	25	6	Caucasian	8	Arthritis, rash, fever, ANA, ↑ anti-dsDNA, anti-SM, RNP, ↓ C3	Yes	No	yes	Yes
15	28	2	Asian	4	Arthritis, fatigue, fever, lymphadenopathy, ANA, pleurisy, Ro, LA, SM and RNP, ↓ C3	Yes	Yes	No	No
16	32	6	Caucasian	2	Arthritis, headache, Ro, LA, ANA, ↑ anti-dsDNA	Yes	No	No	No

aCL, antiocardiolipin antibody; ANCA, antineutrophil cytoplasmic antibody; AZA, azathioprine; BCD, B-cell depletion; BCDT, B-cell depletion treatment; CCP, cyclic citrullinated protein; CYC, cyclophosphamide; dsDNA, double-stranded DNA; LA, anti-La antibody; MMF, mycophenolate mofetil; RNP, anti-ribonucleic antibody; RTX, rituximab; SM, anti-Smith antibody.