Table 2

Median time (months (IQR)) from first record of musculoskeletal and mucocutaneous symptom to date of SLE diagnosis on the CPRD stratified by age at diagnosis and baseline disease severity

Mild-to-moderate diseaseSevere disease
Age groupn (%*)Median months (IQR)n (%*)Median months (IQR)
Time from first musculoskeletal symptom to SLE diagnosis
 0–9 years1 (0.07)0
 10–19 years20 (1.4)6.0 (2.8–27.7)18 (1.3)29.7 (2.3–21.3)
 20–19 years57 (4.0)13.9 (5.1–26.5)15 (1.1)3.8 (1.2–20.6)
 30–39 years122 (8.6)22.2 (7.9–39.9)42 (2.9)14.5 (5.7–37.8)
 40–49 years154 (10.8)28.7 (14.6–46.0)29 (2.0)7.9 (3.8–29.2)
 50–59 years133 (9.3)29.1 (17.5–16.2)45 (3.2)25.6 (10.6–37.3)
 60–69 years83 (5.8)36.1 (15.8–49.6)41 (2.9)34.4 (14.4–45.4)
 70–79 years68 (4.8)30.6 (16.9–49.4)31 (2.2)38.9 (12.7–48.0)
 80+ years21 (1.5)33.9 (18.6–50.4)4 (0.3)44.3 (28.3–49.5)
Time from first mucocutaneous symptom to SLE diagnosis
 0–9 years4 (0.3)7.8 (3.9–12.7)1 (0.07)
 10–19 years15 (1.1)6.5 (1.7–26.1)15 (1.1)23.2 (2.9–45.4)
 20–19 years34 (2.4)17.0 (9.5–45.1)9 (0.6)26.8 (3.5–43.1)
 30–39 years74 (5.2)25.5 (10.2–41.2)24 (1.7)18.9 (6.4–28.2)
 40–49 years116 (8.1)21.4 (9.9–41.7)20 (1.4%)14.3 (2.3–21.8)
 50–59 years65 (4.6)13.5 (5.2–32.4)22 (1.5)20.9 (5.5–38.7)
 60–69 years77 (5.4)17.5 (8.7–36.7)20 (1.4)23.7 (3.8–37.4)
 70–79 years53 (3.7)23.0 (8.1–34.1)16 (1.1)9.7 (3.2–30.1)
 80+ years17 (1.2)16.1 (7.2–28.6)3 (0.2)4.7 (2.8–41.6)
  • *Percentages calculated for all SLE cases (n=1426).

  • CPRD, Clinical Practice Research Database.