Table 1

Associations of serositis in SLE

ReferenceEthnicityNumber of patientsFrequency of
serositis		Associated factors with pleurisy or pericarditis
Mittoo et al15Multiethnic group
(distribution:
64.9% Caucasian,
11.8% Asian
8.6% Afro-Caribbean,
5.7% Aboriginal,
4.8% were of other ethnic descent,
4.2% not reported)		876(Pleurisy)
33.8%		Pleurisy:
higher SDI
(SLICC/ACR Damage
Index Score) (p<0.001),
greater disease duration
(p=0.002),
age at SLE diagnosis
(p=0.009),
anti-Sm (p=0.002),
anti-RNP (p=0.002)
Feng et al11Chinese1790(Pleurisy)
16.6%
(Pericarditis)
9.5%		Pleurisy:
male (p<0.05)
Jeffries et al12Multiethnic group
(distribution:
36.8% European-
Americans,
35.5% African-
Americans,
15.8% Hispanics,
6.6% Gullah African-
Americans,
5.3% American-
Indians)		1251(Pleurisy)
27.4%
(Pericarditis)
19.4%		Pleurisy, pericarditis:
haemolytic anaemia
(p=0.028 for pleurisy, p=0.0019 for pericarditis)
Szodoray et al13Hungarian177(Pericarditis)
23.7%		Pericarditis:
low vitamin D level
(p=0.013)
Tang et al14Chinese917(Pleurisy)
29.7%
(Pericarditis)
11.3%		Pericarditis:
anti-Sm (p=0.002),
anti-Jo-1 (p<0.001)

  • ACR, American College of Rheumatology; SDI, SLICC/ACR Damage Index; SLICC, Systemic Lupus International Collaborating Clinics.