Table 2

Medications associated with hospital admissions among individuals with SLE

Year N=number of admissions2005 N=1782013 N=86P values
Corticosteroid, N (%)143 (79.8)53 (61.6)0.109*
Hydroxychloroquine, N (%)48 (27)51 (59.3)<0.001†
Mycophenolate mofetil or mycophenolic acid, N (%)10 (5.6)11 (12.8)0.610*
Azathioprine, N (%)12 (6.7)8 (9.3)0.497*
Leflunomide, N (%)1 (0.6)8 (9.3)0.488*
Methotrexate, N (%)8 (4.5)6 (7.0)0.719*
Tacrolimus, N (%)7 (3.9)1 (1.2)0.304*
Cyclophosphamide, N (%)4 (2.2)2 (2.3)0.968*
Sirolimus, N (%)3 (1.7)2 (2.3)0.800*
Cyclosporine, N (%)3 (1.7)1 (1.2)0.748†
Rituximab, N (%)3 (1.7)0 (0)0.996†
Belimumab, N (%)0 (0)2 (2.3)0.996†
  • Significance determined via a Poisson* or negative binomial† regression, offset by the number of admissions for each subject.