[HTML][HTML] First and second waves of coronavirus disease-19: A comparative study in hospitalized patients in Reus, Spain

S Iftimie, AF López-Azcona, I Vallverdú… - PloS one, 2021 - journals.plos.org
Many countries have seen a two-wave pattern in reported cases of coronavirus disease-19
during the 2020 pandemic, with a first wave during spring followed by the current second …

Blood letting in high-ferritin type 2 diabetes: effects on insulin sensitivity and β-cell function

JM Fernández-Real, G Penarroja, A Castro… - Diabetes, 2002 - Am Diabetes Assoc
Iron-related insulin-resistance is improved by iron depletion or treatment with iron chelators.
The aim of this study was to evaluate insulin sensitivity and insulin secretion after blood …

Paraoxonases and infectious diseases

J Camps, S Iftimie, A Garcia-Heredia, A Castro… - Clinical …, 2017 - Elsevier
Abstract The paraoxonases (PON1, PON2 and PON3) are an enzyme family with a high
structural homology. All of them have lactonase activity and degrade lipid peroxides in …

Circulating omentin as a novel biomarker of endothelial dysfunction

JM Moreno‐Navarrete, F Ortega, A Castro, M Sabater… - …, 2011 - Wiley Online Library
Omentin is a novel soluble lectin expressed mainly in the stromal‐vascular cells from
visceral adipose tissue with vasodilator effect in isolated blood vessels. To gain insight in the …

Thyroid function is intrinsically linked to insulin sensitivity and endothelium-dependent vasodilation in healthy euthyroid subjects

JM Fernández-Real, A López-Bermejo… - The Journal of …, 2006 - academic.oup.com
Context: Levels of TSH respond to fluctuations in serum free T4 (fT4) but remain in a very
narrow individual range. There exists current controversy regarding the upper limit of normal …

Serum interleukin-6 correlates with endothelial dysfunction in healthy men independently of insulin sensitivity

E Esteve, A Castro, A López-Bermejo, J Vendrell… - Diabetes …, 2007 - Am Diabetes Assoc
OBJECTIVE—Interleukin (IL)-6 is a proinflammatory cytokine that is implicated in the
pathogenesis of atherosclerosis and insulin resistance. Both endothelial dysfunction and …

Machine learning and semi-targeted lipidomics identify distinct serum lipid signatures in hospitalized COVID-19-positive and COVID-19-negative patients

H Castañé, S Iftimie, G Baiges-Gaya… - Metabolism, 2022 - Elsevier
Background Lipids are involved in the interaction between viral infection and the host
metabolic and immunological responses. Several studies comparing the lipidome of COVID …

[HTML][HTML] Risk factors associated with mortality in hospitalized patients with SARS-CoV-2 infection. A prospective, longitudinal, unicenter study in Reus, Spain

S Iftimie, AF López-Azcona, M Vicente-Miralles… - PloS one, 2020 - journals.plos.org
Spain is one of the countries that has suffered the most from the impact of severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), the strain that causes coronavirus …

Adiponectin is associated with vascular function independent of insulin sensitivity

JM Fernández-Real, A Castro, G Vazquez… - Diabetes …, 2004 - Am Diabetes Assoc
OBJECTIVE—Adiponectin has been proposed to play important roles in the regulation of
energy homeostasis and insulin sensitivity. In experimental studies, adiponectin has also …

Blood letting in high-ferritin type 2 diabetes: effects on vascular reactivity

JM Fernández-Real, G Peñarroja, A Castro… - Diabetes …, 2002 - Am Diabetes Assoc
OBJECTIVE—In a recent study, iron chelation with deferoxamine led to improvement of
endothelial dysfunction in patients with coronary artery disease. We tested the hypothesis …