The synovium is the major target tissue of inflammatory arthritides such as rheumatoid
arthritis. The study of synovial tissue has advanced considerably throughout the past few …

SLE is an autoimmune condition characterized by loss of tolerance to chromatin constituents
and the production of ANAs. The majority of SLE patients display spontaneous expression of …

Introduction In 5%–10% of patients with familial Mediterranean fever (FMF), colchicine is not
effective in preventing inflammatory attacks. Another 5%–10% of patients are intolerant to …

Systemic lupus erythematosus (SLE) is an autoimmune disease with marked gender and
ethnic disparities. We report a large transancestral association study of SLE using …

Objective Synovitis is a common feature of rheumatoid arthritis (RA) and systemic lupus
erythematosus (SLE), but the pattern of joint involvement differs in each disease. This study …

NK cell populations were derived from murine splenocytes stimulated by IL-2, IL-15, or the
combination of IL-12 and IL-18. Whereas NK cells derived with the latter cytokines consisted …

Objective: To investigate differences in clinical signs and symptoms, and in antinuclear
antibodies (ANA), between patients with juvenile-onset and adult-onset systemic lupus …

Background Although an early decrease in proteinuria has been correlated with good long-
term renal outcome in lupus nephritis (LN), studies aimed at defining a cut-off proteinuria …

Objective We developed interferon‐α–kinoid (IFN‐K), a drug composed of inactivated IFNα
coupled to a carrier protein, keyhole limpet hemocyanin. In human IFNα–transgenic mice …

A recent genome-wide association study revealed a variant (rs2431697) in an intergenic
region, between the pituitary tumor-transforming 1 (PTTG1) and microRNA (miR-146a) …