User profiles for "author:C Lood"

Christian Lood

- Verified email at uw.edu - Cited by 5754

Cédric Lood

- Verified email at biology.ox.ac.uk - Cited by 1179

[HTML][HTML] Four principles to establish a universal virus taxonomy

…, AJ Lambert, EJ Lefkowitz, M Łobocka, C Lood… - PLoS …, 2023 - journals.plos.org
A universal taxonomy of viruses is essential for a comprehensive view of the virus world and
for communicating the complicated evolutionary relationships among viruses. However …

[HTML][HTML] Cell-free DNA as a biomarker in autoimmune rheumatic diseases

B Duvvuri, C Lood - Frontiers in immunology, 2019 - frontiersin.org
Endogenous DNA is primarily found intracellularly in nuclei and mitochondria. However,
extracellular, cell-free (cf) DNA, has been observed in several pathological conditions …

Neutrophil extracellular traps enriched in oxidized mitochondrial DNA are interferogenic and contribute to lupus-like disease

C Lood, LP Blanco, MM Purmalek… - Nature medicine, 2016 - nature.com
Neutrophil extracellular traps (NETs) are implicated in autoimmunity, but how they are
generated and their roles in sterile inflammation remain unclear. Ribonucleoprotein immune …

[HTML][HTML] Pharmacological importance of optically active tetrahydro-β-carbolines and synthetic approaches to create the C1 stereocenter

AE Laine, C Lood, AMP Koskinen - Molecules, 2014 - mdpi.com
1, 2, 3, 4-Tetrahydro-β-carbolines (THβCs) are a pharmacologically important group of
compounds belonging to the indole alkaloids. C1-Substituted optically active THβCs have …

[HTML][HTML] Abolishment of morphology-based taxa and change to binomial species names: 2022 taxonomy update of the ICTV bacterial viruses subcommittee

D Turner, AN Shkoporov, C Lood, AD Millard… - Archives of …, 2023 - Springer
This article summarises the activities of the Bacterial Viruses Subcommittee of the
International Committee on Taxonomy of Viruses for the period of March 2021− March 2022 …

Neutrophil extracellular traps that are not degraded in systemic lupus erythematosus activate complement exacerbating the disease

…, M Martin, B Gullstrand, H Tydén, C Lood… - The Journal of …, 2012 - journals.aai.org
Ongoing inflammation including activation of the complement system is a hallmark of
systemic lupus erythematosus (SLE). Antimicrobial neutrophil extracellular traps (NETs) are …

Circulating microRNA expression profiles associated with systemic lupus erythematosus

…, AJ Schetter, CT Nielsen, C Lood… - Arthritis & …, 2013 - Wiley Online Library
Objective To evaluate the specificity of expression patterns of cell‐free circulating
microRNAs (miRNAs) in systemic lupus erythematosus (SLE). Methods Total RNA was …

[HTML][HTML] Combination of pre-adapted bacteriophage therapy and antibiotics for treatment of fracture-related infection due to pandrug-resistant Klebsiella pneumoniae

A Eskenazi, C Lood, J Wubbolts, M Hites… - Nature …, 2022 - nature.com
A 30-year-old bombing victim with a fracture-related pandrug-resistant Klebsiella
pneumoniae infection after long-term (> 700 days) antibiotic therapy is treated with a pre …

[HTML][HTML] Bacteriophage-antibiotic combination therapy against extensively drug-resistant Pseudomonas aeruginosa infection to allow liver transplantation in a toddler

…, D Van der Linden, O Chatzis, C Lood… - Nature …, 2022 - nature.com
Post-operative bacterial infections are a leading cause of mortality and morbidity after
ongoing liver transplantation. Bacteria causing these infections in the hospital setting can …

Neutrophil calprotectin identifies severe pulmonary disease in COVID-19

…, NL Lugogo, RJ Woods, C Lood… - Journal of Leucocyte …, 2021 - academic.oup.com
Severe cases of coronavirus disease 2019 (COVID-19) are regularly complicated by
respiratory failure. Although it has been suggested that elevated levels of blood neutrophils …