[HTML][HTML] Four principles to establish a universal virus taxonomy
A universal taxonomy of viruses is essential for a comprehensive view of the virus world and
for communicating the complicated evolutionary relationships among viruses. However …
for communicating the complicated evolutionary relationships among viruses. However …
[HTML][HTML] Cell-free DNA as a biomarker in autoimmune rheumatic diseases
Endogenous DNA is primarily found intracellularly in nuclei and mitochondria. However,
extracellular, cell-free (cf) DNA, has been observed in several pathological conditions …
extracellular, cell-free (cf) DNA, has been observed in several pathological conditions …
Neutrophil extracellular traps enriched in oxidized mitochondrial DNA are interferogenic and contribute to lupus-like disease
C Lood, LP Blanco, MM Purmalek… - Nature medicine, 2016 - nature.com
Neutrophil extracellular traps (NETs) are implicated in autoimmunity, but how they are
generated and their roles in sterile inflammation remain unclear. Ribonucleoprotein immune …
generated and their roles in sterile inflammation remain unclear. Ribonucleoprotein immune …
[HTML][HTML] Pharmacological importance of optically active tetrahydro-β-carbolines and synthetic approaches to create the C1 stereocenter
AE Laine, C Lood, AMP Koskinen - Molecules, 2014 - mdpi.com
1, 2, 3, 4-Tetrahydro-β-carbolines (THβCs) are a pharmacologically important group of
compounds belonging to the indole alkaloids. C1-Substituted optically active THβCs have …
compounds belonging to the indole alkaloids. C1-Substituted optically active THβCs have …
[HTML][HTML] Abolishment of morphology-based taxa and change to binomial species names: 2022 taxonomy update of the ICTV bacterial viruses subcommittee
This article summarises the activities of the Bacterial Viruses Subcommittee of the
International Committee on Taxonomy of Viruses for the period of March 2021− March 2022 …
International Committee on Taxonomy of Viruses for the period of March 2021− March 2022 …
Neutrophil extracellular traps that are not degraded in systemic lupus erythematosus activate complement exacerbating the disease
…, M Martin, B Gullstrand, H Tydén, C Lood… - The Journal of …, 2012 - journals.aai.org
Ongoing inflammation including activation of the complement system is a hallmark of
systemic lupus erythematosus (SLE). Antimicrobial neutrophil extracellular traps (NETs) are …
systemic lupus erythematosus (SLE). Antimicrobial neutrophil extracellular traps (NETs) are …
Circulating microRNA expression profiles associated with systemic lupus erythematosus
…, AJ Schetter, CT Nielsen, C Lood… - Arthritis & …, 2013 - Wiley Online Library
Objective To evaluate the specificity of expression patterns of cell‐free circulating
microRNAs (miRNAs) in systemic lupus erythematosus (SLE). Methods Total RNA was …
microRNAs (miRNAs) in systemic lupus erythematosus (SLE). Methods Total RNA was …
[HTML][HTML] Combination of pre-adapted bacteriophage therapy and antibiotics for treatment of fracture-related infection due to pandrug-resistant Klebsiella pneumoniae
A Eskenazi, C Lood, J Wubbolts, M Hites… - Nature …, 2022 - nature.com
A 30-year-old bombing victim with a fracture-related pandrug-resistant Klebsiella
pneumoniae infection after long-term (> 700 days) antibiotic therapy is treated with a pre …
pneumoniae infection after long-term (> 700 days) antibiotic therapy is treated with a pre …
[HTML][HTML] Bacteriophage-antibiotic combination therapy against extensively drug-resistant Pseudomonas aeruginosa infection to allow liver transplantation in a toddler
…, D Van der Linden, O Chatzis, C Lood… - Nature …, 2022 - nature.com
Post-operative bacterial infections are a leading cause of mortality and morbidity after
ongoing liver transplantation. Bacteria causing these infections in the hospital setting can …
ongoing liver transplantation. Bacteria causing these infections in the hospital setting can …
Neutrophil calprotectin identifies severe pulmonary disease in COVID-19
Severe cases of coronavirus disease 2019 (COVID-19) are regularly complicated by
respiratory failure. Although it has been suggested that elevated levels of blood neutrophils …
respiratory failure. Although it has been suggested that elevated levels of blood neutrophils …