Multifaceted effects of hydroxychloroquine in human disease

NJ Olsen, MA Schleich, DR Karp - Seminars in Arthritis and Rheumatism, 2013 - Elsevier
Objectives Hydroxychloroquine (HCQ) is a widely used medication for the treatment of
rheumatoid arthritis and systemic lupus erythematosus. An increasing body of evidence …

Autoantibodies and SLE—the threshold for disease

NJ Olsen, DR Karp - Nature Reviews Rheumatology, 2014 - nature.com
The presence of autoantibodies in apparently healthy individuals has been increasingly
recognized. Although some of these individuals are in preclinical stages of a disease such …

The lupus family registry and repository

A Rasmussen, S Sevier, JA Kelly, SB Glenn… - …, 2011 - academic.oup.com
Abstract The Lupus Family Registry and Repository (LFRR) was established with the goal of
assembling and distributing materials and data from families with one or more living …

American College of rheumatology clinical guidance for multisystem inflammatory syndrome in children associated with SARS–CoV‐2 and Hyperinflammation in …

LA Henderson, SW Canna, KG Friedman… - Arthritis & …, 2021 - Wiley Online Library
Objective To provide guidance on the management of Multisystem Inflammatory Syndrome
in Children (MIS‐C), a condition characterized by fever, inflammation, and multiorgan …

American College of Rheumatology clinical guidance for multisystem inflammatory syndrome in children associated With SARS–CoV‐2 and hyperinflammation in …

LA Henderson, SW Canna, KG Friedman… - Arthritis & …, 2020 - Wiley Online Library
Objective To provide guidance on the management of multisystem inflammatory syndrome
in children (MIS‐C), a condition characterized by fever, inflammation, and multiorgan …

[HTML][HTML] Transancestral mapping and genetic load in systemic lupus erythematosus

CD Langefeld, HC Ainsworth, DSC Graham… - Nature …, 2017 - nature.com
Systemic lupus erythematosus (SLE) is an autoimmune disease with marked gender and
ethnic disparities. We report a large transancestral association study of SLE using …

Restorative justice in school communities

DR Karp, B Breslin - Youth & Society, 2001 - journals.sagepub.com
In response to recent school violence, most schools in the United States have adopted
increasingly punitive disciplinary policies. However, some schools have embraced …

American College of Rheumatology clinical guidance for multisystem inflammatory syndrome in children associated with SARS–CoV‐2 and hyperinflammation in …

LA Henderson, SW Canna, KG Friedman… - Arthritis & …, 2022 - Wiley Online Library
Objective To provide guidance on the management of Multisystem Inflammatory Syndrome
in Children (MIS‐C), a condition characterized by fever, inflammation, and multiorgan …

[HTML][HTML] SLE peripheral blood B cell, T cell and myeloid cell transcriptomes display unique profiles and each subset contributes to the interferon signature

AM Becker, KH Dao, BK Han, R Kornu, S Lakhanpal… - PloS one, 2013 - journals.plos.org
Systemic lupus erythematosus (SLE) is a chronic autoimmune disease that is characterized
by defective immune tolerance combined with immune cell hyperactivity resulting in the …

Phase II randomized trial of rituximab plus cyclophosphamide followed by belimumab for the treatment of lupus nephritis

Y Atisha‐Fregoso, S Malkiel, KM Harris… - Arthritis & …, 2021 - Wiley Online Library
Objective To assess the safety, mechanism of action, and preliminary efficacy of rituximab
followed by belimumab in the treatment of refractory lupus nephritis (LN). Methods In a …