Systemic lupus erythematosus (SLE) is the paradigm of systemic autoimmune diseases
characterised by a wide spectrum of clinical manifestations with an unpredictable relapsing …

Lupus nephritis (LN) is a severe manifestation of SLE, characterised by subendothelial
and/or subepithelial immune complex depositions in the afflicted kidney, resulting in …

During the COVID-19 pandemic, the need to provide high-level care for a large number of
patients with COVID-19 has affected resourcing for, and limited the routine care of, all other …

Objective To report the 10-year follow-up of the MAINTAIN Nephritis Trial comparing
azathioprine (AZA) and mycophenolate mofetil (MMF) as maintenance therapy of …

Background Although an early decrease in proteinuria has been correlated with good long-
term renal outcome in lupus nephritis (LN), studies aimed at defining a cut-off proteinuria …

Objectives In patients with LN, clinical and histological responses to treatment have been
shown to be discordant. We investigated whether per-protocol repeat kidney biopsies are …

Systemic lupus erythematosus is a chronic autoimmune disease characterized by loss of
tolerance against nuclear and cytoplasmic self-antigens, induction of immunity and tissue …

Objective The Euro‐Lupus regimen of low‐dose intravenous cyclophosphamide (IV
CYC)(cumulative dose of 3 gm) was developed to reduce gonadal toxicity. To address the …

Lupus nephritis (LN) is a frequent and severe manifestation of systemic lupus
erythematosus. The main goal of the management of LN is to avoid chronic kidney disease …

The concept of progressive fibrosing interstitial lung disease (PF-ILD) has recently emerged.
However, real-life proportion of PF-ILDs outside IPF is still hard to evaluate. Therefore, we …