Sterile particles induce robust inflammatory responses that underlie the pathogenesis of
diseases like silicosis, gout, and atherosclerosis. A key cytokine mediating this response is …

Fine tuning of the protein folding environment in subcellular organelles, such as
mitochondria, is important for adaptive homeostasis and may participate in human diseases …

Cytosolic DNA-sensing pathways that signal via Stimulator of interferon genes (STING)
mediate immunity to pathogens and also promote autoimmune pathology in DNaseII-and …

The sterile inflammatory response to cell death and irritant crystals is medically important
because it causes disease. Although these stimuli are structurally distinct, they cause …

Sterile particles cause several chronic, inflammatory diseases, characterized by repeating
cycles of particle phagocytosis and inflammatory cell death. Recent studies have proposed …

We present non-cytotoxic, magnetic, Arg-Gly-Asp (RGD)-functionalized nickel nanowires
(RGD–nanowires) that trigger specific cellular responses via integrin transmembrane …

Discussion| We identified decreases of in situ and invasive melanoma diagnoses during
2020, primarily among older, male, and non-Hispanic White patients. Incidence rates of …

Hidradenitis suppurativa (HS) is a chronic, debilitating skin condition that disproportionately
affects socioeconomically underserved patients. Currently, treatment outcomes for patients …

Primary cutaneous nasal-type NK/T-cell lymphoma presenting as purpuric nodules on the lower
leg - ScienceDirect Skip to main contentSkip to article Elsevier logo Journals & Books Search …

Discussion The presentation of CBM can be diagnostically challenging, as illustrated by the
subtle lesion described in this report. Classically, CBM presents acutely, most often on the …