Hepatic manifestations in systemic lupus erythematosus

…, M Cruz-Contreras, J Merayo-Chalico… - Lupus, 2020 - journals.sagepub.com
Systemic lupus erythematosus (SLE) is a multi-organic autoimmune disease with a wide
variety of clinical manifestations. However, hepatic dysfunction is not included in the …

Lymphopenia and autoimmunity: a double-edged sword

J Merayo-Chalico, S Rajme-López, A Barrera-Vargas… - Human Immunology, 2016 - Elsevier
Lymphopenia is strongly associated with autoimmune diseases. The molecular mechanisms
that link both phenomena are still unclear, but certain key pathways have been described …

Neutrophil-mediated carbamylation promotes articular damage in rheumatoid arthritis

…, D Sandoval-Heglund, J Merayo-Chalico… - Science …, 2020 - science.org
Formation of autoantibodies to carbamylated proteins (anti-CarP) is considered detrimental
in the prognosis of erosive rheumatoid arthritis (RA). The source of carbamylated antigens …

Posterior reversible encephalopathy syndrome: a neuropsychiatric manifestation of systemic lupus erythematosus

…, A Arauz, A Barrera-Vargas, J Merayo-Chalico - Autoimmunity …, 2021 - Elsevier
Abstract Posterior Reversible Encephalopathy Syndrome (PRES) is an acute neurological
syndrome clinically characterized by seizures, altered mental status, headache, and visual …

Neutrophil extracellular trap-associated carbamylation and histones trigger osteoclast formation in rheumatoid arthritis

…, A Barrera-Vargas, J Merayo-Chalico… - Annals of the …, 2023 - ard.bmj.com
Objective Neutrophil infiltration into the synovial joint is a hallmark of rheumatoid arthritis
(RA), a disease characterised by progressive bone erosion. However, the mechanisms by …

Lymphopenia as risk factor for development of severe infections in patients with systemic lupus erythematosus: a case–control study

J Merayo-Chalico, D Gómez-Martín… - … Journal of Medicine, 2013 - academic.oup.com
Objectives: Hematological abnormalities, particularly lymphopenia, are common in patients
with systemic lupus erythematosus (SLE), whether the disease is active or not. The aim of …

Differential ubiquitination in NETs regulates macrophage responses in systemic lupus erythematosus

…, C Carmona-Rivera, J Merayo-Chalico… - Annals of the …, 2018 - ard.bmj.com
Objectives To assess if ubiquitinated proteins potentially present in neutrophil extracellular
traps (NETs) can modify cellular responses and induce inflammatory mechanisms in …

Factors associated with mortality and infections in patients with systemic lupus erythematosus with diffuse alveolar hemorrhage

…, J Alcocer-Varela, J Merayo-Chalico… - The Journal of …, 2014 - jrheum.org
Objective. To evaluate factors associated with mortality and infections in patients with
systemic lupus erythematosus (SLE) and diffuse alveolar hemorrhage (DAH). Methods. A …

Common hematological values predict unfavorable outcomes in hospitalized COVID-19 patients

…, G Domínguez-Cherit, J Merayo-Chalico… - Clinical …, 2021 - Elsevier
COVID-19 can range from asymptomatic to life-threatening. Early identification of patients
who will develop severe disease is crucial. A number of scores and indexes have been …

Clinical outcomes and risk factors for posterior reversible encephalopathy syndrome in systemic lupus erythematosus: a multicentric case–control study

J Merayo-Chalico, E Apodaca… - Journal of Neurology …, 2016 - jnnp.bmj.com
Background Posterior reversible encephalopathy syndrome (PRES) is a well-known but rare
complication in patients (< 1%) with systemic lupus erythematosus (SLE). However, current …