Infection with Burkholderia mallei (formerly Pseudomonas mallei) can cause a
subcutaneous infection known as farcy or can disseminate to cause the condition known as …

Summary Background Black and Hispanic children living in urban environments in the USA
have an excess burden of morbidity and mortality from asthma. Therapies directed at the …

Patients with acute respiratory distress syndrome are at increased risk for developing
multiorgan system dysfunction. The goal of this study was to establish an in vivo murine …

Neuropilin-1 (Npn-1) is a cell surface receptor that binds vascular endothelial growth factor
(VEGF), a potent mediator of endothelial permeability, chemotaxis, and proliferation. In vitro …

The IMPACC cohort, composed of> 1,000 hospitalized COVID-19 participants, contains five
illness trajectory groups (TGs) during acute infection (first 28 days), ranging from milder (TG1 …

The Immunophenotyping Assessment in a COVID-19 Cohort (IMPACC) is a prospective
longitudinal study designed to enroll 1000 hospitalized patients with COVID-19 …

The mechanisms responsible for the divergent physiological responses of endothelial cells
to vascular endothelial growth factor (VEGF) are incompletely understood. We hypothesized …

Background Despite well-known susceptibilities to other respiratory viral infections,
individuals with allergic asthma have shown reduced susceptibility to severe coronavirus …

Background Severe COVID-19 is associated with innate immunopathology, and CD14, a
proximal activator of innate immunity, has been suggested as a potential therapeutic target …

Introduction Both clinical experience and experimental evidence have suggested that
Adrenocorticotropic hormone (ACTH) might directly exert immunomodulatory effects not …