Biomarkers in systemic lupus erythematosus: challenges and prospects for the future

CC Liu, AH Kao, S Manzi… - Therapeutic advances in …, 2013 - journals.sagepub.com
The search for lupus biomarkers to diagnose, monitor, stratify, and predict individual
response to therapy is currently more intense than ever before. This effort is essential for …

Derivation and validation of the Systemic Lupus International Collaborating Clinics classification criteria for systemic lupus erythematosus

M Petri, AM Orbai, GS Alarcón, C Gordon… - Arthritis & …, 2012 - Wiley Online Library
Abstract Objective The Systemic Lupus International Collaborating Clinics (SLICC) group
revised and validated the American College of Rheumatology (ACR) systemic lupus …

Age-specific incidence rates of myocardial infarction and angina in women with systemic lupus erythematosus: comparison with the Framingham Study

S Manzi, EN Meilahn, JE Rairie… - American journal of …, 1997 - academic.oup.com
The authors ascertained cardiovascular events (myocardial infarction and angina pectoris)
in 498 women with systemic lupus erythematosus seen at the University of Pittsburgh …

Mortality in systemic lupus erythematosus

S Bernatsky, JF Boivin, L Joseph… - … : Official Journal of …, 2006 - Wiley Online Library
Objective To examine mortality rates in the largest systemic lupus erythematosus (SLE)
cohort ever assembled. Methods Our sample was a multisite international SLE cohort (23 …

Update on vascular disease in systemic lupus erythematosus

AH Kao, JM Sabatine, S Manzi - Current opinion in rheumatology, 2003 - journals.lww.com
Our focus on the causes of vascular disease in systemic lupus erythematosus must now
include nontraditional risk factors such as immune and inflammatory mediators. With the …

Biomarkers for systemic lupus erythematosus

JM Ahearn, CC Liu, AH Kao, S Manzi - Translational Research, 2012 - Elsevier
The urgent need for lupus biomarkers was demonstrated in September 2011 during a
Workshop sponsored by the Food and Drug Administration: Potential Biomarkers Predictive …

[HTML][HTML] Association of Systemic Lupus Erythematosus with C8orf13–BLK and ITGAM–ITGAX

G Hom, RR Graham, B Modrek, KE Taylor… - … England Journal of …, 2008 - Mass Medical Soc
Background Systemic lupus erythematosus (SLE) is a clinically heterogeneous disease in
which the risk of disease is influenced by complex genetic and environmental contributions …

A large-scale replication study identifies TNIP1, PRDM1, JAZF1, UHRF1BP1 and IL10 as risk loci for systemic lupus erythematosus

V Gateva, JK Sandling, G Hom, KE Taylor, SA Chung… - Nature …, 2009 - nature.com
Genome-wide association studies have recently identified at least 15 susceptibility loci for
systemic lupus erythematosus (SLE). To confirm additional risk loci, we selected SNPs from …

Prevalence and risk factors of carotid plaque in women with systemic lupus erythematosus

S Manzi, F Selzer, K Sutton‐Tyrrell… - … : Official Journal of …, 1999 - Wiley Online Library
Objective To determine the prevalence of carotid atherosclerosis and associated risk factors
in women with systemic lupus erythematosus (SLE). Methods Carotid plaque and intima …

The effect of combined estrogen and progesterone hormone replacement therapy on disease activity in systemic lupus erythematosus: a randomized trial

JP Buyon, MA Petri, MY Kim, KC Kalunian… - Annals of internal …, 2005 - acpjournals.org
Background: There is concern that exogenous female hormones may worsen disease
activity in women with systemic lupus erythematosus (SLE). Objective: To evaluate the effect …