User profiles for "author:V Kakkar"

Vandita Kakkar

University Institute of Pharmaceutical Sciences, Panjab University, Chandigarh
Verified email at pu.ac.in
Cited by 2829

Potential of solid lipid nanoparticles in brain targeting

IP Kaur, R Bhandari, S Bhandari, V Kakkar - Journal of Controlled release, 2008 - Elsevier
Brain is a delicate organ, isolated from general circulation and characterized by the
presence of relatively impermeable endothelial cells with tight junctions, enzymatic activity …

Impact of MCP-1 in atherosclerosis

J Lin, V Kakkar, X Lu - Current pharmaceutical design, 2014 - ingentaconnect.com
Monocyte chemotactic protein-1 (MCP-1)(also referred to as chemokine (CC motif) ligand 2
(CCL2) is expressed by mainly inflammatory cells and endothelial cells. The expression …

Barcoding heat shock proteins to human diseases: looking beyond the heat shock response

V Kakkar, M Meister-Broekema… - Disease models & …, 2014 - journals.biologists.com
There are numerous human diseases that are associated with protein misfolding and the
formation of toxic protein aggregates. Activating the heat shock response (HSR)–and thus …

Natural history of postoperative deep-vein thrombosis

VV Kakkar, CT Howe, C Flanc, MB Clarke - The Lancet, 1969 - Elsevier
Abstract 132 consecutive patients were investigated during the postoperative period using
the 125 I-labelled fibrinogen test to detect deep-vein thrombosis in the legs. Thrombosis …

Impaired myocardial angiogenesis and ischemic cardiomyopathy in mice lacking the vascular endothelial growth factor isoforms VEGF164 and VEGF188

P Carmeliet, YS Ng, D Nuyens, G Theilmeier… - Nature medicine, 1999 - nature.com
Fig. 1 Targeting of the VEGF gene. a, Modification of the VEGF gene. Top box, Targeting
vector pPNT. VEGF120 and wildtype VEGF allele (WT VEGF). Middle box, Homologously …

Deep vein thrombosis of the leg: is there a “high risk” group?

VV Kakkar, CT Howe, AN Nicolaides… - The American Journal of …, 1970 - Elsevier
Two hundred and three patients undergoing elective surgery were investigated to determine
the group of patients who are at a “great risk” of developing deep vein thrombosis. It was …

Low molecular weight versus standard heparin for prevention of venous thromboembolism after major abdominal surgery

VV Kakkar, AT Cohen, RA Edmonson, MJ Phillips… - The Lancet, 1993 - Elsevier
Low-molecular-weight heparin (LMWH) is effective in the prevention of postoperative
venous thromboembolism but does it have the safety advantages over standard heparin …

Lipid peroxides and atherosclerosis.

MD Stringer, PG Görög, A Freeman, VV Kakkar - British Medical Journal, 1989 - bmj.com
Plasma lipid peroxide concentrations were measured in 100 patients with occlusive arterial
disease proved angiographically (50 patients with ischaemic heart disease, 50 with …

Plasminogen activation initiated by single-chain urokinase-type plasminogen activator: potentiation by U937 monocytes

V Ellis, MF Scully, VV Kakkar - Journal of Biological Chemistry, 1989 - Elsevier
The binding of urokinase-type plasminogen activators (u-PA) to receptors on various cell
types has been proposed to be an important feature of many cellular processes requiring …

The origin of deep vein thrombosis: a venographic study

AN Nicolaides, VV Kakkar, ES Field… - The British journal of …, 1971 - birpublications.org
A venographic technique has been described which demonstrates the soleal veins in
addition to the rest of the deep veins of the lower limb consistently in the presence or …