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Value of repeat biopsy in lupus nephritis flares
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    Biological change or poor measurement instrument?

    Dear Editors,

    We read with great interest the article of Greloni et al, "Value of repeat biopsy in lupus nephritis flares" and have some comments.

    There is a high probability that what they call "histologic transformation" is further evidence of the poor reproducibility of the interpretation of the renal biopsy in lupus nephritis and no evidence that there really been a change in the biological phenomenon o...

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