Article Text

Download PDFPDF

LP-023 Systemic lupus erythematosus concomitant with atopic dermatitis, a case series report
  1. Seon Young Song,
  2. Hae Chang Joh,
  3. Ki Yeon Kim,
  4. Mihn Sook Jue,
  5. Jeong Eun Kim and
  6. Joo Yeon Ko
  1. Department of Dermatology, Hanyang University College of Medicine, Seoul, Korea, Republic of Korea


Description Systemic lupus erythematosus (SLE) and atopic dermatitis (AD) are both immune disorders that can lead to significant physical complications. There have been several reports of coexistence or association of the two diseases. In cases of concurrence of SLE and AD, patients may require more comprehensive therapeutic strategies for proper control of both diseases’ activities. In addition, physical trauma such as excoriation can exacerbate or initiate cutaneous lupus erythematosus lesions, so called Koebner phenomenon.

Herein, we report 12 patients with SLE accompanied with AD. They commonly presented with eczematous lesions or lichenification of the flexural areas with marked itching. They all showed elevation of immunoglobulin E (IgE) level, thus satisfying the diagnostic criteria for AD. Additionally, ANA titer and Anti-dsDNA antibody were elevated in laboratory tests. Also, they satisfied other diagnostic criteria for SLE, such as acute or chronic cutaneous lupus erythematosus. Under the diagnosis of concurrent AD and SLE, they were successfully controlled for both cutaneous lupus erythematosus and chronic pruritic eczema.

Conclusions If patients with SLE suffer from severe itching that is incompatible with the activity of SLE, it can be helpful to measure IgE levels. Elevated IgE levels may indicate their underlying allergic disorders, especially AD. It is important to screen for other diagnostic criteria for AD in addition to measuring IgE levels. Understanding the coexistence of both conditions allows the physician to provide optimal treatment for the patient. Herein, we report a case series of SLE patients with concurrent AD who show elevated IgE level.

  • Atopic dermatitis

This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See:

Statistics from

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.