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  • O15 B cell, T cell, cytotoxic/NK cell, and mitochondrial gene dysregulation patterns separate neuropsychiatric systemic lupus erythematosus patients into two distinct subgroups with differential anticipated response to targeted therapies

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O15 B cell, T cell, cytotoxic/NK cell, and mitochondrial gene dysregulation patterns separate neuropsychiatric systemic lupus erythematosus patients into two distinct subgroups with differential anticipated response to targeted therapies

Authors

  • Julius Lindblom Division of Rheumatology, Dept. of Medicine Solna, Karolinska Institutet and Karolinska University Hospital, Stockholm, Sweden PubMed articlesGoogle scholar articles
  • Dionysis Nikolopoulos Division of Rheumatology, Dept. of Medicine Solna, Karolinska Institutet and Karolinska University Hospital, Stockholm, Sweden PubMed articlesGoogle scholar articles
  • Daniel Toro-Domínguez GENYO, Centre for Genomics and Oncological Research: Pfizer, University of Granada/Andalusian Regional Government, Granada, Spain, Medical Genomics, Granada, Spain PubMed articlesGoogle scholar articles
  • Elena Carnero-Montoro GENYO, Centre for Genomics and Oncological Research: Pfizer, University of Granada/Andalusian Regional Government, Granada, Spain, Medical Genomics, Granada, Spain PubMed articlesGoogle scholar articles
  • Maria Orietta Borghi Dept. of Clinical Sciences and Community Health, Università Degli Studi di Milano, Milan, Italy IRCCS, Istituto Auxologico Italiano, Milan, Italy PubMed articlesGoogle scholar articles
  • Jessica Castillo Dept. of Biomedical Engineering, University of Houston, Houston, TX, USA PubMed articlesGoogle scholar articles
  • Ellen Iacobaeus Neuroimmunology Unit, Dept. of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden PubMed articlesGoogle scholar articles
  • Yvonne Enman Division of Rheumatology, Dept. of Medicine Solna, Karolinska Institutet and Karolinska University Hospital, Stockholm, Sweden PubMed articlesGoogle scholar articles
  • PRECISESADS Clinical Consortium
    Google scholar articles
  • Chandra Mohan Dept. of Biomedical Engineering, University of Houston, Houston, TX, USA PubMed articlesGoogle scholar articles
  • Lorenzo Beretta Referral Center for Systemic Autoimmune Diseases, Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico di Milano, Italy PubMed articlesGoogle scholar articles
  • Marta E Alarcón-Riquelme GENYO, Centre for Genomics and Oncological Research: Pfizer, University of Granada/Andalusian Regional Government, Granada, Spain, Medical Genomics, Granada, Spain Institute of Environmental Medicine, Karolinska Institute, Stockholm, Sweden PubMed articlesGoogle scholar articles
  • Guillermo Barturen GENYO, Centre for Genomics and Oncological Research: Pfizer, University of Granada/Andalusian Regional Government, Granada, Spain, Medical Genomics, Granada, Spain Dept. of Genetics, Faculty of Sciences, University of Granada, Granada, Spain PubMed articlesGoogle scholar articles
  • Ioannis Parodis Division of Rheumatology, Dept. of Medicine Solna, Karolinska Institutet and Karolinska University Hospital, Stockholm, Sweden Dept. of Rheumatology, Faculty of Medicine and Health, Örebro University, Örebro, Sweden PubMed articlesGoogle scholar articles

Citation

Lindblom J, Nikolopoulos D, Toro-Domínguez D, et al
O15 B cell, T cell, cytotoxic/NK cell, and mitochondrial gene dysregulation patterns separate neuropsychiatric systemic lupus erythematosus patients into two distinct subgroups with differential anticipated response to targeted therapies
Lupus Science & Medicine 2024;11:doi: 10.1136/lupus-2024-el.25

Publication history

  • First published March 14, 2024.
Online issue publication 
March 15, 2024

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© Author(s) (or their employer(s)) 2022. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. http://creativecommons.org/licenses/by-nc/4.0/ This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ .