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37 Post-transplantation management
  1. Y.K. Onno Teng
  1. Leiden University Medical Center, The Netherlands

Abstract

Systemic lupus erythematosus (SLE) is a complex autoimmune disorder that frequently involves the kidneys and can ultimately lead to renal replacement therapy or kidney transplantation for severe cases. Lifelong prevalence of end-stage kidney disease (ESKD) in SLE patients is 10–15%.1 Therefore, although SLE is a rare disease, managing lupus patients after a kidney transplantation is even more rare and presents with its unique challenges. In this presentation I will address general aspects of care after kidney transplantation and then focus on SLE disease recurrence, graft rejection and complications from immunosuppressive therapy.

Reference

  1. Hocaoğlu M, Valenzuela-Almada MO, Dabit JY, et al. Incidence, prevalence, and mortality of lupus nephritis: a population-based study over four decades using the lupus midwest network. Arthritis Rheumatol. 2023;75(4):567–73. doi: 10.1002/art.42375.

Learning Objectives At the end of this presentation participants will be able to:

  • Explain the impact of SLE on kidney function and the potential need for kidney transplantation

  • Discuss the risks and challenges associated with SLE recurrence after kidney transplantation

  • Explain the potential complications associated with immunosuppressive therapy used after transplantation

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