Lupus Science & Medicine: 2 (1)

Animal models

Significantly reduced lymphadenopathy, salivary gland infiltrates and proteinuria in MRL-lpr/lpr mice treated with ultrasoluble curcumin/turmeric: increased survival with curcumin treatment
(8 September, 2015)
Biji T Kurien, Valerie M Harris, Syed M S Quadri, Patricia Coutinho-de Souza, Joshua Cavett, Amanda Moyer, Bilal Ittiq, Angela Metcalf, Husayn F Ramji, Dat Truong, Ramesh Kumar, Kristi A Koelsch, Mike Centola, Adam Payne, Debashish Danda, R Hal Scofield

Biomarker studies

Association of the interferon signature metric with serological disease manifestations but not global activity scores in multiple cohorts of patients with SLE (30 March, 2015)
William P Kennedy, Romeo Maciuca, Kristen Wolslegel, Wei Tew, Alexander R Abbas, Christina Chaivorapol, Alyssa Morimoto, Jacqueline M McBride, Paul Brunetta, Bruce C Richardson, John C Davis, Timothy W Behrens, Michael J Townsend
Brain metabolism and autoantibody titres predict functional impairment in systemic lupus erythematosus (30 March, 2015)
Meggan Mackay, Chris C Tang, Bruce T Volpe, Cynthia Aranow, Paul J Mattis, Ricki A Korff, Betty Diamond, David Eidelberg
BAFF (B cell activating factor) transcript level in peripheral blood of patients with SLE is associated with same-day disease activity as well as global activity over the next year (18 June, 2015)
Eric Zollars, Jadwiga Bienkowska, Julie Czerkowicz, Norm Allaire, Ann M Ranger, Laurence Magder, Michelle Petri

Brief communication

Redefining cutaneous lupus erythematosus: a proposed international consensus approach and results of a preliminary questionnaire (26 March, 2015)
J F Merola, F Nyberg, F Furukawa, M J Goodfield, M Hasegawa, B Marinovic, J Szepietowski, J Dutz, V P Werth
A proteinuria cut-off level of 0.7 g/day after 12 months of treatment best predicts long-term renal outcome in lupus nephritis: data from the MAINTAIN Nephritis Trial
(12 November, 2015)
Farah Tamirou, Bernard R Lauwerys, Maria Dall'Era, Meggan Mackay, Brad Rovin, Ricard Cervera, Frédéric A Houssiau
Pharmacodynamic monitoring of (immuno)proteasome inhibition during bortezomib treatment of a critically ill patient with lupus nephritis and myocarditis (18 December, 2015)
Karina A de Groot, Michel Tsang a Sjoe, Denise Niewerth, Jacqueline Cloos, Jonathan L Blank, Hans W M Niessen, Sonja Zweegman, Alexandre E Voskuyl, Gerrit Jansen, Joost W van der Heijden

Clinical trials and drug discovery

Standard medical care of patients with systemic lupus erythematosus (SLE) in large specialised centres: data from the Russian Federation, Ukraine and Republic of Kazakhstan (ESSENCE) (19 February, 2015)
E Nasonov, S Soloviev, J E Davidson, A Lila, G Togizbayev, R Ivanova, Ch Baimukhamedov, Zh Omarbekova, O Iaremenko, A Gnylorybov, S Shevchuk, A Vasylyev, M H S Pereira
Association of low vitamin D with high disease activity in an Australian systemic lupus erythematosus cohort (8 April, 2015)
K S Yap, M Northcott, A B-Y Hoi, EF Morand, M Nikpour
Safety and efficacy of hCDR1 (Edratide) in patients with active systemic lupus erythematosus: results of phase II study (11 August, 2015)
Murray B Urowitz, David A Isenberg, Daniel J Wallace

Dialogue

Dialogue: Vitamin D, statins and atherosclerotic progression in paediatric lupus (6 February, 2015)
Gary Gilkeson, Sue Manzi
Dialogue: A blissful future for lupus nephritis: harnessing repeat kidney biopsies to identify meaningful biomarkers of disease (1 April, 2015)
Fernanda Payan Schober, William F Pendergraft
Dialogue: Cutaneous lupus erythematosus: a lone Wolf? (1 April, 2015)
Andrew G Franks, Antonio Guilabert
Dialogue: Early predictors of long-term lupus nephritis outcomes: looking into the future (2 June, 2015)
Derek M Fine

Epidemiology and outcomes

Work disability, lost productivity and associated risk factors in patients diagnosed with systemic lupus erythematosus (20 January, 2015)
Tammy O Utset, Amrutha Baskaran, Barbara M Segal, Laura Trupin, Sarika Ogale, Ellen Herberich, Kenneth Kalunian
Preliminary test of the LFA rapid evaluation of activity in lupus (LFA-REAL): an efficient outcome measure correlates with validated instruments (4 March, 2015)
Anca Askanase, Xiaoqing Li, Avery Pong, Katrina Shum, Stan Kamp, Fredonna Carthen, Teresa Aberle, Leslie Hanrahan, Paola Daly, Jon Giles, Joan T Merrill
Effect of corticosteroid use by dose on the risk of developing organ damage over time in systemic lupus erythematosus—the Hopkins Lupus Cohort (11 March, 2015)
Sarah Al Sawah, Xiang Zhang, Baojin Zhu, Laurence S Magder, Shonda A Foster, Noriko Iikuni, Michelle Petri
Patients with overlap autoimmune disease differ from those with ‘pure’ disease (6 May, 2015)
Michael D Lockshin, Alana B Levine, Doruk Erkan
Characteristics of azathioprine use and cessation in a longitudinal lupus cohort (20 August, 2015)
Lucy Croyle, Alberta Hoi, Eric F Morand
Perceptions of racism in healthcare among patients with systemic lupus erythematosus: a cross-sectional study (20 August, 2015)
Ernest R Vina, Leslie R M Hausmann, Tammy O Utset, Christopher M Masi, Kimberly P Liang, C Kent Kwoh
Systemic lupus erythematosus complicated by diffuse alveolar haemorrhage: risk factors, therapy and survival (23 September, 2015)
Nayef M Kazzaz, Patrick Coit, Emily E Lewis, W Joseph McCune, Amr H Sawalha, Jason S Knight
Factors associated with pain coping and catastrophising in patients with systemic lupus erythematosus: a cross-sectional study of the LuLa-cohort (12 November, 2015)
Julia Fischin, Gamal Chehab, Jutta G Richter, Rebecca Fischer-Betz, Borgi Winkler-Rohlfing, Reinhart Willers, Matthias Schneider
Outcome of patients with autoimmune diseases in the intensive care unit: a mixed cluster analysis (1 December, 2015)
Santiago Bernal-Macías, Benjamín Reyes-Beltrán, Nicolás Molano-González, Daniel Augusto Vega, Claudia Bichernall, Luis Aurelio Díaz, Adriana Rojas-Villarraga, Juan-Manuel Anaya

Genetics

DNA methylation patterns in naïve CD4+ T cells identify epigenetic susceptibility loci for malar rash and discoid rash in systemic lupus erythematosus (15 September, 2015)
Paul Renauer, Patrick Coit, Matlock A Jeffries, Joan T Merrill, W Joseph McCune, Kathleen Maksimowicz-McKinnon, Amr H Sawalha

Lupus nephritis

Evaluation of B lymphocyte stimulator and a proliferation inducing ligand as candidate biomarkers in lupus nephritis based on clinical and histopathological outcome following induction therapy (22 January, 2015)
Ioannis Parodis, Agneta Zickert, Birgitta Sundelin, Magnus Axelsson, Jakob Gerhardsson, Elisabet Svenungsson, Vivianne Malmström, Iva Gunnarsson
Identification of clinical and serological factors during induction treatment of lupus nephritis that are associated with renal outcome (20 May, 2015)
Maria Dall'Era, Victoria Levesque, Neil Solomons, Matt Truman, David Wofsy
Influence of renal complications on the efficacy and adverse events of tacrolimus combination therapy in patients with systemic lupus erythematosus (SLE) during a maintenance phase: a single-centre, prospective study (29 May, 2015)
Sho Ishii, Yusuke Miwa, Kumiko Otsuka, Shinichiro Nishimi, Airi Nishimi, Mayu Saito, Yoko Miura, Nao Oguro, Takahiro Tokunaga, Ryo Takahashi, Tsuyoshi Kasama
Characterising the immune profile of the kidney biopsy at lupus nephritis flare differentiates early treatment responders from non-responders (18 November, 2015)
Samir V Parikh, Ana Malvar, Huijuan Song, Valeria Alberton, Bruno Lococo, Jay Vance, Jianying Zhang, Lianbo Yu, Brad H Rovin

Reproductive health and APS

Lupus anticoagulant, disease activity and low complement in the first trimester are predictive of pregnancy loss (9 December, 2015)
Anil Mankee, Michelle Petri, Laurence S Magder

Review

Haematological manifestations of lupus (3 March, 2015)
Anum Fayyaz, Ann Igoe, Biji T Kurien, Debashish Danda, Judith A James, Haraldine A Stafford, R Hal Scofield
A highlight from the LUPUS 2014 meeting: eight great ideas (30 June, 2015)
Jill P Buyon, Phillip Cohen, Joan T Merrill, Gary Gilkeson, Mariana Kaplan, Judith James, W Joseph McCune, Sasha Bernatsky, Keith Elkon

Corrections

Correction (2 February, 2015) Free
Correction (9 March, 2015) Free

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Table of contents

2015 - Volume 2 - 1

Animal models

Biomarker studies

Brief communication

Clinical trials and drug discovery

Dialogue

Epidemiology and outcomes

Genetics

Lupus nephritis

Reproductive health and APS

Review

Corrections

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Table of contents

2015 - Volume 2 - 1

Animal models

Biomarker studies

Brief communication

Clinical trials and drug discovery

Dialogue

Epidemiology and outcomes

Genetics

Lupus nephritis

Reproductive health and APS

Review

Corrections