GG-02 Epigenetic reprogramming in NAïVE CD4+ T cells favouring T cell activation and NON-TH1 effector T cell immune response as an early event in lupus flares

Patrick Coit; Mikhail G Dozmorov; Joan T Merrill; W Joseph McCune; Kathleen Maksimowicz-McKinnon; Jonathan D Wren; Amr H Sawalha

doi:10.1136/lupus-2016-000179.54

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Genetics, Genomics and Epigenetics

GG-02 Epigenetic reprogramming in NAïVE CD4+ T cells favouring T cell activation and NON-TH1 effector T cell immune response as an early event in lupus flares

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Patrick Coit 1Division of Rheumatology, Department of Internal Medicine, University of Michigan, Ann Arbour, Michigan, USA PubMed articles Google scholar articles
Mikhail G Dozmorov 2Department of Biostatistics, Virginia Commonwealth University, Richmond, Virginia, USA PubMed articles Google scholar articles
Joan T Merrill 3Clinical Pharmacology Program, Oklahoma Medical Research Foundation, Oklahoma City, Oklahoma, USA PubMed articles Google scholar articles
W Joseph McCune 1Division of Rheumatology, Department of Internal Medicine, University of Michigan, Ann Arbour, Michigan, USA PubMed articles Google scholar articles
Kathleen Maksimowicz-McKinnon 4Division of Rheumatology, Henry Ford Health System, Detroit, Michigan, USA PubMed articles Google scholar articles
Jonathan D Wren 5Arthritis and Clinical Immunology Program, Oklahoma Medical Research Foundation, Oklahoma City, Oklahoma, USA6Department of Biochemistry and Molecular Biology, The University of Oklahoma Health Sciences Centre, Oklahoma City, Oklahoma, USA PubMed articles Google scholar articles
Amr H Sawalha 1Division of Rheumatology, Department of Internal Medicine, University of Michigan, Ann Arbour, Michigan, USA7Centre for Computational Medicine and Bioinformatics, University of Michigan, Ann Arbour, Michigan, USA PubMed articles Google scholar articles

Citation

Coit P, Dozmorov MG, Merrill JT, et al

GG-02 Epigenetic reprogramming in NAïVE CD4+ T cells favouring T cell activation and NON-TH1 effector T cell immune response as an early event in lupus flares

Lupus Science & Medicine 2016;3:doi: 10.1136/lupus-2016-000179.54

Publication history

First published August 31, 2016.

Online issue publication

September 01, 2016

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