Lupus Science & Medicine: 4 (1)

Review

Current and future therapies for SLE: obstacles and recommendations for the development of novel treatments (17 December, 2017)
Zahi Touma, Dafna D Gladman
Cell-bound complement activation products in SLE (21 August, 2017)
Rosalind Ramsey-Goldman, Jian Li, Thierry Dervieux, Roberta Vezza Alexander

Biomarker studies

Original research article: Osteopontin is associated with disease severity and antiphospholipid syndrome in well characterised Swedish cases of SLE (28 July, 2017)
Lina Wirestam, Martina Frodlund, Helena Enocsson, Thomas Skogh, Jonas Wetterö, Christopher Sjöwall
Original research article: Identification of biomarkers of response to abatacept in patients with SLE using deconvolution of whole blood transcriptomic data from a phase IIb clinical trial (28 July, 2017)
Somnath Bandyopadhyay, Sean E Connolly, Omar Jabado, June Ye, Sheila Kelly, Michael A Maldonado, Rene Westhovens, Peter Nash, Joan T Merrill, Robert M Townsend

Co-morbidities

Original research article: Cardiovascular risk profiles in a lupus cohort: what do different calculators tell us? (28 July, 2017)
Daniel Boulos, Rachel L Koelmeyer, Eric F Morand, Alberta Y Hoi

Genetics

Original research article: Single-cell gene expression patterns in lupus monocytes independently indicate disease activity, interferon and therapy (25 June, 2017)
Zhongbo Jin, Wei Fan, Mark A Jensen, Jessica M Dorschner, George F Bonadurer, Danielle M Vsetecka, Shreyasee Amin, Ashima Makol, Floranne Ernste, Thomas Osborn, Kevin Moder, Vaidehi Chowdhary, Timothy B Niewold

Lupus nephritis

Lupus-related single nucleotide polymorphisms and risk of diffuse large B-cell lymphoma (12 November, 2017)
Sasha Bernatsky, Héctor A Velásquez García, John J Spinelli, Patrick Gaffney, Karin E Smedby, Rosalind Ramsey-Goldman, Sophia S Wang, Hans-Olov Adami, Demetrius Albanes, Emanuele Angelucci, Stephen M Ansell, Yan W Asmann, Nikolaus Becker, Yolanda Benavente, Sonja I Berndt, Kimberly A Bertrand, Brenda M Birmann, Heiner Boeing, Paolo Boffetta, Paige M Bracci, Paul Brennan, Angela R Brooks-Wilson, James R Cerhan, Stephen J Chanock, Jacqueline Clavel, Lucia Conde, Karen H Cotenbader, David G Cox, Wendy Cozen, Simon Crouch, Anneclaire J De Roos, Silvia de Sanjose, Simonetta Di Lollo, W Ryan Diver, Ahmet Dogan, Lenka Foretova, Hervé Ghesquières, Graham G Giles, Bengt Glimelius, Thomas M Habermann, Corinne Haioun, Patricia Hartge, Henrik Hjalgrim, Theodore R Holford, Elizabeth A Holly, Rebecca D Jackson, Rudolph Kaaks, Eleanor Kane, Rachel S Kelly, Robert J Klein, Peter Kraft, Anne Kricker, Qing Lan, Charles Lawrence, Mark Liebow, Tracy Lightfoot, Brian K Link, Marc Maynadie, James McKay, Mads Melbye, Thierry J Molina, Alain Monnereau, Lindsay M Morton, Alexandra Nieters, Kari E North, Anne J Novak, Kenneth Offit, Mark P Purdue, Marco Rais, Jacques Riby, Eve Roman, Nathaniel Rothman, Gilles Salles, Gianluca Severi, Richard K Severson, Christine F Skibola, Susan L Slager, Alex Smith, Martyn T Smith, Melissa C Southey, Anthony Staines, Lauren R Teras, Carrie A Thompson, Hervé Tilly, Lesley F Tinker, Anne Tjonneland, Jenny Turner, Claire M Vajdic, Roel C H Vermeulen, Joseph Vijai, Paolo Vineis, Jarmo Virtamo, Zhaoming Wang, Stephanie Weinstein, Thomas E Witzig, Andrew Zelenetz, Anne Zeleniuch-Jacquotte, Yawei Zhang, Tongzhang Zheng, Mariagrazia Zucca, Ann E Clarke
Original research article: Safety, pharmacokinetics and pharmacodynamics of AMG 811, an anti-interferon-γ monoclonal antibody, in SLE subjects without or with lupus nephritis (14 September, 2017)
Michael J Boedigheimer, David A Martin, Zahir Amoura, Jorge Sánchez-Guerrero, Juanita Romero-Diaz, Alan Kivitz, Cynthia Aranow, Tak Mao Chan, Yip Boon Chong, Kit Chiu, Christine Wang, Winnie Sohn, Gregory E Arnold, Michael A Damore, Andrew A Welcher, Barbara A Sullivan, Brian L Kotzin, James B Chung
Early proteinuria response: a valid real-life situation predictor of long-term lupus renal outcome in an ethnically diverse group with severe biopsy-proven nephritis? (12 June, 2017)
Michelle R Ugolini-Lopes, Luciana Parente C Seguro, Maitê Xavier F Castro, Danielle Daffre, Alex C Lopes, Eduardo F Borba, Eloisa Bonfá

Editorial

The role of microparticles in the pathogenesis of SLE: a new look at an old paradigm (6 October, 2017)
David Pisetsky
Observational studies on glucocorticoids are harmful! (7 April, 2017)
Maarten Boers

Brief communication

Correlation of hypogammaglobulinaemia with proteinuria, and the relationship between hypogammaglobulinaemia and infection in active lupus nephritis (31 August, 2017)
Dawn Elaine Smilek, Noha Lim, Linna Ding, Sara G. Murray, Betty Diamond, David Wofsy
Predictors of peripheral arterial disease in SLE change with patient’s age (12 January, 2017)
Jose-Gabriel Erdozain, Irama Villar, Javier Nieto, Ioana Ruiz-Arruza, Guillermo Ruiz-Irastorza
Use of SLICC criteria in a large, diverse lupus registry enables SLE classification of a subset of ACR-designated subjects with incomplete lupus (17 March, 2017)
Teresa Aberle, Rebecka L Bourn, Hua Chen, Virginia C Roberts, Joel M Guthridge, Krista Bean, Julie M Robertson, Kathy L Sivils, Astrid Rasmussen, Meghan Liles, Joan T Merrill, John B Harley, Nancy J Olsen, David R Karp, Judith A James

Case report

Topical drug-induced subacute cutaneous lupus erythematosus isolated to the hands (13 March, 2017)
Sarika M Ramachandran, Jonathan S Leventhal, Loren G Franco, Adnan Mir, Ruth F Walters, Andrew G Franks

Clinical trials and drug discovery

Original research article: Repository corticotropin injection in patients with persistently active SLE requiring corticosteroids: post hoc analysis of results from a two-part, 52-week pilot study (27 December, 2017)
Richard A Furie, Margaret Mitrane, Enxu Zhao, Patrice M Becker
The use of rituximab in newly diagnosed patients with systemic lupus erythematosus: long-term steroid saving capacity and clinical effectiveness (2 February, 2017)
Borja Gracia-Tello, Amara Ezeonyeji, David Isenberg

Epidemiology and outcomes

Original research article: Illness representations of systemic lupus erythematosus and systemic sclerosis: a comparison of patients, their rheumatologists and their general practitioners (14 November, 2017)
Seher Arat, Jan L Lenaerts, Ellen De Langhe, Patrick Verschueren, Philip Moons, Joris Vandenberghe, Veerle Taelman, Rene Westhovens
Original research article: Associates and predictors of pleurisy or pericarditis in SLE (23 October, 2017)
Seungwon Ryu, Wei Fu, Michelle A Petri
Original research article: Strong viral associations with SLE among Filipinos (28 July, 2017)
Evan S Vista, Michael H Weisman, Mariko L Ishimori, Hua Chen, Rebecka L Bourn, Ben F Bruner, Laniyati Hamijoyo, Robelle D Tanangunan, Noga J Gal, Julie M Robertson, John B Harley, Joel M Guthridge, Sandra V Navarra, Judith A James
Clinicians approaches to management of background treatment in patients with SLE in clinical remission: results of an international observational survey (29 June, 2017)
Pintip Ngamjanyaporn, Eoghan M McCarthy, Jamie C Sergeant, John Reynolds, Sarah Skeoch, Benjamin Parker, Ian N Bruce
Original research: Complement levels and risk of organ involvement in patients with systemic lupus erythematosus (25 June, 2017)
Ignacio Javier Gandino, Marina Scolnik, Emmanuel Bertiller, Valeria Scaglioni, Luis Jose Catoggio, Enrique Roberto Soriano
Predictors of incident proteinuria among patients with SLE (22 May, 2017)
Alí Duarte-García, Erik Barr, Laurence S Magder, Michelle Petri
Is frailty a relevant concept in SLE? (1 February, 2017)
Patricia P Katz, James Andrews, Jinoos Yazdany, Gabriela Schmajuk, Laura Trupin, Edward Yelin
Disease activity patterns over time in patients with SLE: analysis of the Hopkins Lupus Cohort (8 February, 2017)
Noémi Györi, Ioanna Giannakou, Katerina Chatzidionysiou, Laurence Magder, Ronald F van Vollenhoven, Michelle Petri
Presentation of SLE in UK primary care using the Clinical Practice Research Datalink (10 February, 2017)
Alison L Nightingale, Julie E Davidson, Charles T Molta, Hong J Kan, Neil J McHugh

Immunology and inflammation

Ultrasound detects subclinical joint inflammation in the hands and wrists of patients with systemic lupus erythematosus without musculoskeletal symptoms (19 January, 2017)
Carina A Ruano, Rui Malheiro, João F Oliveira, Sofia Pinheiro, Luís S Vieira, Maria Francisca Moraes-Fontes
Surface complement C3 fragments and cellular binding of microparticles in patients with SLE (31 March, 2017)
Line Kjær Winberg, Claus Henrik Nielsen, Søren Jacobsen

Meeting report

Outcomes in mothers with rheumatic diseases and their offspring workshop (22 February, 2017)
Autumn Neville, Sasha Bernatsky, Bindee Kuriya, Emmanuel Bujold, Eliza Chakravarty, Robert W Platt, Anick Bérard, Évelyne Vinet

Correction

Correction: Single-cell gene expression patterns in lupus monocytes independently indicate disease activity, interferon and therapy (11 September, 2017)

Reviewers

Thank you to our reviewers 2016 (21 August, 2017) Free

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Table of contents

2017 - Volume 4 - 1

Review

Biomarker studies

Co-morbidities

Genetics

Lupus nephritis

Editorial

Brief communication

Case report

Clinical trials and drug discovery

Epidemiology and outcomes

Immunology and inflammation

Meeting report

Correction

Reviewers

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Table of contents

2017 - Volume 4 - 1

Review

Biomarker studies

Co-morbidities

Genetics

Lupus nephritis

Editorial

Brief communication

Case report

Clinical trials and drug discovery

Epidemiology and outcomes

Immunology and inflammation

Meeting report

Correction

Reviewers