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PS3:56 The association between self-reported physical activity on disease status patients with systemic lupus erythematosus: data from korean lupus network (kornet) registry
  1. S Kim,
  2. J Choe,
  3. S Park and
  4. H Lee
  1. Catholic University of Daegu School of Medicine, Daegu, South Korea


Objective The aim of this study was to identify the influence of physical activity on disease activity and damage in systemic lupus erythematosus (SLE).

Methods A total of 464 patients with Sjögren’s syndrome were consecutively enrolled from KORean lupus Network (KORNET) registry. This registry assessed clinical features, disease activity (Systemic Lupus Erythematosus Disease Activity Index 2000 [SLEDAI-2K]), and disease damage (Systemic Lupus International Collaborating Clinics/American College of Rheumatology [SLICC/ACR] damage index) at the enrollment of study. Self-reported physical activity was measured by international physical activity questionnaire (IPAQ). Statistical analyses were used by Spearman’s correlation and Mann-Whitney U test.

Results The median total physical activity (MET-minute/day) was 1173.0 (IQR 396.0–2772.0). There is significant difference of vigour activity between patients with lupus nephritis (n=110) and without lupus nephritis (n=354) (p=0.048), but not total, moderate, and walking activities. Among total patients, total IPAQ score was marginally associated with SLEDAI and SLICC/ACR scores (r=−0.142, p=0.008 and r=−0.104, p=0.026). Higher SLICC/ACR scores was associated with lower walking activity and total activity of IPAQ in patients with lupus nephritis, (r=−0.256, p=0.007 and r=−0.193, p=0.044, respectively).

Conclusion This study showed that self-reported physical activity might be in part associated with disease activity and damage in patients with SLE.

  • Systemic Lupus Erythematosus
  • Physical Activity

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