AI-09 T follicular helper (Tfh) cells are increased in asymptomatic anti-nuclear antibody (ANA)+ individuals and appear to play a role in epitope spreading

Joan Wither; Nan-Hua Chang; Sindhu R Johnson; Waleed Hafiz; Kieran Manion; Dario Ferri; Ariana Karanxha; Babak Noamani; Dennisse Bonilla; Sina Rusta-Sellehy; Larissa Lisnevskaia; Zahi Touma; Earl Silverman; Arthur Bookman; Carolina Landolt-Marticorena; Yuriy Baglaenko

doi:10.1136/lupus-2018-lsm.9

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Adaptive Immunity

AI-09 T follicular helper (Tfh) cells are increased in asymptomatic anti-nuclear antibody (ANA)⁺ individuals and appear to play a role in epitope spreading

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Joan Wither 1Krembil Research Institute, University Health Network, Toronto, Canada 2Department of Immunology, University of Toronto, Toronto, Canada 3Division of Rheumatology, University Health Network, Toronto, Canada 4Department of Medicine, University of Toronto, Toronto, Canada PubMed articles Google scholar articles
Nan-Hua Chang 1Krembil Research Institute, University Health Network, Toronto, Canada PubMed articles Google scholar articles
Sindhu R Johnson 3Division of Rheumatology, University Health Network, Toronto, Canada 4Department of Medicine, University of Toronto, Toronto, Canada 5Division of Rheumatology, Mount Sinai Hospital, Toronto, Canada 6Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, Canada PubMed articles Google scholar articles
Waleed Hafiz 3Division of Rheumatology, University Health Network, Toronto, Canada PubMed articles Google scholar articles
Kieran Manion 1Krembil Research Institute, University Health Network, Toronto, Canada 2Department of Immunology, University of Toronto, Toronto, Canada PubMed articles Google scholar articles
Dario Ferri 1Krembil Research Institute, University Health Network, Toronto, Canada 2Department of Immunology, University of Toronto, Toronto, Canada PubMed articles Google scholar articles
Ariana Karanxha 1Krembil Research Institute, University Health Network, Toronto, Canada PubMed articles Google scholar articles
Babak Noamani 1Krembil Research Institute, University Health Network, Toronto, Canada PubMed articles Google scholar articles
Dennisse Bonilla 1Krembil Research Institute, University Health Network, Toronto, Canada PubMed articles Google scholar articles
Sina Rusta-Sellehy 1Krembil Research Institute, University Health Network, Toronto, Canada PubMed articles Google scholar articles
Larissa Lisnevskaia 7Lakeridge Heath Services, Oshawa, Canada PubMed articles Google scholar articles
Zahi Touma 3Division of Rheumatology, University Health Network, Toronto, Canada 4Department of Medicine, University of Toronto, Toronto, Canada PubMed articles Google scholar articles
Earl Silverman 8Division of Rheumatology, Sick Children’s Hospital, Toronto, Canada 9Department of Pediatrics, University of Toronto, Toronto, Canada PubMed articles Google scholar articles
Arthur Bookman 3Division of Rheumatology, University Health Network, Toronto, Canada 4Department of Medicine, University of Toronto, Toronto, Canada PubMed articles Google scholar articles
Carolina Landolt-Marticorena 1Krembil Research Institute, University Health Network, Toronto, Canada PubMed articles Google scholar articles
Yuriy Baglaenko 1Krembil Research Institute, University Health Network, Toronto, Canada 2Department of Immunology, University of Toronto, Toronto, Canada PubMed articles Google scholar articles

Citation

Wither J, Chang N, Johnson SR, et al

AI-09 T follicular helper (Tfh) cells are increased in asymptomatic anti-nuclear antibody (ANA)⁺ individuals and appear to play a role in epitope spreading

Lupus Science & Medicine 2018;5:doi: 10.1136/lupus-2018-lsm.9

Publication history

First published September 4, 2018.

Online issue publication

May 13, 2022

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