Lupus Science & Medicine: 6 (1)

Brief communication

Effect of vitamin D on serum markers of bone turnover in SLE in a randomised controlled trial (17 September, 2019)
Sara K. Tedeschi, Cynthia Aranow, Diane L. Kamen, Meryl LeBoff, Betty Diamond, Karen H. Costenbader
Jaccoud’s arthropathy in SLE: findings from a Latin American multiethnic population (12 August, 2019)
Rosana Quintana, Guillermo Pons-Estel, Karen Roberts, Monica Sacnún, Guillermo Berbotto, Mercedes A Garcia, Veronica Saurit, Leonor Barile-Fabris, Eduardo M Acevedo-Vazquez, João C Tavares Brenol, Emilia I Sato, Antonio Iglesias, Oscar Uribe, Graciela Alarcon, Bernardo A Pons-Estel
Iatrogenic antibody deficiency from B-cell targeted therapies in autoimmune rheumatic diseases (30 July, 2019)
Sonali Wijetilleka, David Jayne, Chetan Mukhtyar, Mohammed Yousuf Karim
Varicella zoster virus infections increase the risk of disease flares in patients with SLE: a matched cohort study (29 July, 2019)
Fangfang Sun, Yi Chen, Wanlong Wu, Li Guo, Wenwen Xu, Jie Chen, Shuhui Sun, Jiajie Li, Zhiwei Chen, Liyang Gu, Xiaodong Wang, Ting Li, Shuang Ye
Prevalence of coronary artery calcification in young patients with SLE of predominantly Hispanic and African–American descent (29 June, 2019)
Yevgeniya Gartshteyn, Genna Braverman, Sharan Mahtani, Laura Geraldino-Pardilla, Sabahat Bokhari, Anca Askanase
Measuring plasma C4D to monitor immune complexes in lupus nephritis (3 June, 2019)
Tineke Kraaij, Sara C. Nilsson, Cees van Kooten, Marcin Okrój, Anna M Blom, YK Onno Teng
Hydroxychloroquine usage in US patients, their experiences of tolerability and adherence, and implications for treatment: survey results from 3127 patients with SLE conducted by the Lupus Foundation of America (19 March, 2019)
Daniel J Wallace, Karin Tse, Leslie Hanrahan, Rupert Davies, Michelle A Petri
Constitutive reduction in the checkpoint inhibitor, CTLA-4, does not accelerate SLE in NZM 2328 mice (19 February, 2019)
William Stohl, Ning Yu, Samantha A Chalmers, Chaim Putterman, Chaim O Jacob

Biomarker studies

Original research: Differential expression of antibodies to NMDA receptor in anti-NMDA receptor encephalitis and in neuropsychiatric systemic lupus erythematosus (13 November, 2019)
Shunsei Hirohata, Keiko Tanaka
Original research: Randomised prospective trial to assess the clinical utility of multianalyte assay panel with complement activation products for the diagnosis of SLE (19 September, 2019)
Daniel J Wallace, Roberta Vezza Alexander, Tyler O'Malley, Arezou Khosroshahi, Mehrnaz Hojjati, Konstantinos Loupasakis, Jeffrey Alper, Yvonne Sherrer, Maria Fondal, Rajesh Kataria, Tami Powell, Claudia Ibarra, Sonali Narain, Elena Massarotti, Arthur Weinstein, Thierry Dervieux
Original research: Comparison of PREDICTS atherosclerosis biomarker changes after initiation of new treatments in patients with SLE (27 June, 2019)
Maureen McMahon, Brian Skaggs, Jennifer Grossman, Weng Kee Wong, Lori Sahakian, Weiling Chen, Bevra Hahn
Urine TWEAK level as a biomarker for early response to treatment in active lupus nephritis: a prospective multicentre study (9 April, 2019)
Thitima Benjachat Suttichet, Wonngarm Kittanamongkolchai, Chutipha Phromjeen, Sirirat Anutrakulchai, Thanachai Panaput, Atiporn Ingsathit, Nanticha Kamanamool, Vuddhidej Ophascharoensuk, Vasant Sumethakul, Yingyos Avihingsanon
Platelet-bound C4d, low C3 and lupus anticoagulant associate with thrombosis in SLE (30 March, 2019)
Michelle A Petri, John Conklin, Tyler O'Malley, Thierry Dervieux

Childhood lupus

Original research:
Elevated serum complement levels and higher gene copy number of complement C4B are associated with hypertension and effective response to statin therapy in childhood-onset systemic lupus erythematosus (SLE)
(31 July, 2019)
Evan Mulvihill, Stacy Ardoin, Susan D Thompson, Bi Zhou, Gakit Richard Yu, Emily King, Nora Singer, D M Levy, Hermine Brunner, Yee Ling Wu, Haikady N Nagaraja, Laura Eve Schanberg, Chack-Yung Yu

Co-morbidities

Original research: Autoantibody clustering of lupus-associated pulmonary hypertension (2 December, 2019)
Marisa Mizus, Jessica Li, Daniel Goldman, Michelle A Petri
Original research: Association of lipoprotein subfractions and glycoprotein acetylation with coronary plaque burden in SLE (12 July, 2019)
Monica M Purmalek, Philip M Carlucci, Amit K Dey, Maureen Sampson, Yenealem Temesgen-Oyelakin, Simantini Sakhardande, Joseph B Lerman, Alice Fike, Michael Davis, Jonathan H Chung, Taufiq Salahuddin, Zerai Manna, Sarthak Gupta, Marcus Y Chen, Sarfaraz Hasni, Nehal N Mehta, Alan Remaley, Mariana J Kaplan

Case report

Low hydroxychloroquine blood levels in patients who have had gastric bypass surgery (16 June, 2019)
Donald E Thomas, Jonathan S Lyons, Barry S Greene, Michelle A Petri

Clinical trials and drug discovery

Original research:
First use of cenerimod, a selective S1P₁ receptor modulator, for the treatment of SLE: a double-blind, randomised, placebo-controlled, proof-of-concept study
(9 November, 2019)
Viktoria Hermann, Anastas Batalov, Svetlana Smakotina, Pierre-Eric Juif, Peter Cornelisse
Original research: SLE clinical trials: impact of missing data on estimating treatment effects (3 October, 2019)
Mimi Kim, Joan T Merrill, Cuiling Wang, Shankar Viswanathan, Ken Kalunian, Leslie Hanrahan, Peter Izmirly

Cutaneous lupus

Original research: Population-based prevalence and incidence estimates of primary discoid lupus erythematosus from the Manhattan Lupus Surveillance Program (30 October, 2019)
Peter Izmirly, Jill Buyon, H Michael Belmont, Sara Sahl, Isabella Wan, Jane Salmon, Anca Askanase, Joan M Bathon, Laura Geraldino-Pardilla, Yousaf Ali, Ellen Ginzler, Chaim Putterman, Caroline Gordon, Charles Helmick, Hilary Parton
Original research: Plucked hair follicles from patients with chronic discoid lupus erythematosus show a disease-specific molecular signature (14 July, 2019)
Mohammad Shalbaf, Adewonuola A Alase, Anna Berekmeri, Md Yuzaiful Md Yusof, Jelena Pistolic, Mark J Goodfield, Sara Edward, Natalia V Botchkareva, Martin Stacey, Edward M Vital, Miriam Wittmann

Epidemiology and outcomes

Original research: Scoring systemic lupus erythematosus (SLE) disease activity with simple, rapid outcome measures (30 December, 2019)
Aikaterini Thanou, Judith A James, Cristina Arriens, Teresa Aberle, Eliza Chakravarty, Joseph Rawdon, Stavros Stavrakis, Joan T Merrill, Anca Askanase
Original research: Development of a systemic lupus erythematosus cardiovascular risk equation (10 October, 2019)
Michelle A Petri, Erik Barr, Laurence S Magder
Original research: Patient perceptions and preferences of biologic therapies in SLE (12 August, 2019)
S Sam Lim, Hong Kan, Bonnie F Pobiner, Gaobin Bao, Cristina Drenkard
Original research: Marital status and age of systemic lupus erythematous diagnosis: the potential for differences related to sex and gender (5 August, 2019)
Eugene Brailovski, Evelyne Vinet, Christian A Pineau, Jennifer Lee, Luck Lukusa, Fares Kalache, Louis-Pierre Grenier, Deborah DaCosta, Sasha Bernatsky
Original research: Global consensus building and prioritisation of fundamental lupus challenges: the ALPHA project (19 July, 2019)
Susan Manzi, Sandra Raymond, Karin Tse, Yaritza Peña, Annick Anderson, Kathleen Arntsen, Sang-Cheol Bae, Ian Bruce, Thomas Dörner, Kenneth Getz, Leslie Hanrahan, Amy Kao, Eric Morand, Brad Rovin, Laura Eve Schanberg, Joan M Von Feldt, Victoria P Werth, Karen Costenbader
Original research: Assessing cognitive impairment in SLE: examining relationships between resting glucose metabolism and anti-NMDAR antibodies with navigational performance (11 July, 2019)
Elisabeth Ploran, Chris Tang, Meggan Mackay, Michael Small, Erik Anderson, Justin Storbeck, Brittany Bascetta, Simran Kang, Cynthia Aranow, Carl Sartori, Philip Watson, Bruce Volpe, Betty Diamond, David Eidelberg
Cell of origin in diffuse large B-cell lymphoma in systemic lupus erythematosus: molecular and clinical factors associated with survival (4 May, 2019)
Basile Tessier-Cloutier, David DW Twa, Eva Baecklund, Randy Gascoyne, Nathalie A Johnson, Carin Backlin, Diane L Kamen, Ann E Clarke, Rosalind Ramsey-Goldman, Jennifer LF Lee, Pedro Farinha, Sasha Bernatsky

Immunology and inflammation

Original research: Belatacept in kidney transplant patients with systemic lupus erythematosus (22 December, 2019)
Irene Carrión-Barberà, Melissa Fajardo, George Danias, Demetra Tsapepas, Yevgeniya Gartshteyn, Hilda Fernandez, Anca Askanase
Original research: Cervus and cucumis peptides ameliorates bone erosion in experimental arthritis by inhibiting osteoclastogenesis (12 May, 2019)
Ze-Min Lin, Yu-Ting Liu, Yan-Sheng Xu, Xiao-Qian Yang, Feng-Hua Zhu, Wei Tang, Shi-Jun He, Jian-Ping Zuo
L-sepiapterin restores SLE serum-induced markers of endothelial function in endothelial cells (19 February, 2019)
Joy N Jones Buie, Dorea Pleasant Jenkins, Robin Muise-Helmericks, Jim C Oates

Lupus nephritis

Outcome of participants with nephrotic syndrome in combined clinical trials of lupus nephritis (4 February, 2019)
Liliana Michelle Gomez Mendez, Matthew D Cascino, Tamiko R Katsumoto, Paul Brakeman, Paul Brunetta, David Jayne, Maria Dall’Era, Brad Rovin, Jay Garg

Review

Interferon pathway in SLE: one key to unlocking the mystery of the disease (13 August, 2019)
Lars Rönnblom, Dag Leonard
Single-cell RNA sequencing for the study of lupus nephritis (4 June, 2019)
Evan Der, Hemant Suryawanshi, Jill Buyon, Thomas Tuschl, Chaim Putterman
Type I interferons in host defence and inflammatory diseases (28 May, 2019)
Mary K. Crow, Lars Ronnblom
Review: Changing paradigms in the treatment of systemic lupus erythematosus (8 February, 2019)
Antonis Fanouriakis, George Bertsias
SLE: reconciling heterogeneity (4 February, 2019)
Michael D Lockshin, Medha Barbhaiya, Peter Izmirly, Jill P Buyon, Mary K Crow
10 most important contemporary challenges in the management of SLE (10 January, 2019)
Renaud Felten, Flora Sagez, Pierre-Edouard Gavand, Thierry Martin, Anne-Sophie Korganow, Christelle Sordet, Rose-Marie Javier, Pauline Soulas-Sprauel, Marianne Rivière, Florence Scher, Vincent Poindron, Aurélien Guffroy, Laurent Arnaud

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Table of contents

2019 - Volume 6 - 1

Brief communication

Biomarker studies

Childhood lupus

Co-morbidities

Case report

Clinical trials and drug discovery

Cutaneous lupus

Epidemiology and outcomes

Immunology and inflammation

Lupus nephritis

Review

Correction

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Table of contents

2019 - Volume 6 - 1

Brief communication

Biomarker studies

Childhood lupus

Co-morbidities

Case report

Clinical trials and drug discovery

Cutaneous lupus

Epidemiology and outcomes

Immunology and inflammation

Lupus nephritis

Review

Correction