Article Text

Download PDFPDF

P148 A study of disease profile of adult and juvenile lupus patients at disease onset at tertiary care centre of Northern India
  1. Neeraj Jain1,
  2. Lalit Duggal1,
  3. Sujata Sawhney2,
  4. Manjari Agarawal2,
  5. Jeet Kumar Patel1 and
  6. Mayank Gupta1
  1. 1Dept. of Rheumatology, Sir Ganga Ram Hospital, New Delhi
  2. 2Dept. of Pediatric Rheumatology, Sir Ganga Ram Hospital, New Delhi, India


Background Systemic Lupus Erythematosus (SLE) is a chronic autoimmune disease. It may affect adults and paediatric patients and may have different organ involvement at onset of disease.

Objectives To study disease profile of 100 adult and paediatric SLE patients at disease onset to find any significant difference in organ involvement in both cohorts.

Method 100 adult and 100 paediatric patients who classified SLE-SLICC criteria were recruited in study after taking consent at tertiary care centre in northern India. Demographic data and clinical profiles were recorded. Fisher’s test was used to find p value and p value less than 0.05 was taken as statistical significance.

Results Out of 100 patients, females were 85% in adult cohort Vs 76% in paediatric cohort. Median delay in diagnosis was more with adult than paediatric cases. Lupus nephritis, mouth ulcers, NPSLE was common in paediatric SLE patients. In adult cohort, there was significant association for fatigue, RP, and thrombosis.

Abstract P148 Table 1

Conclusion Major organ involvement was frequent in adult patients while arthritis, leukopenia, low complements, more positivity of anti-dsDNA, APLA antibodies positivity were significantly common in paediatric cases.

Statistics from

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.