1508 Single-cell epigenetic profiling highlights genetic impact on chromatin accessibility in SLE

Sai Ma; Richard C Pelikan; Yao Fu; Jennifer A Kelly; David Murphy; Graham B Wiley; Vinay K Kartha; Caleb Lareau; Jason D Buenrostro; Patrick M Gaffney

doi:10.1136/lupus-2021-lupus21century.91

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1508 Single-cell epigenetic profiling highlights genetic impact on chromatin accessibility in SLE

Authors

Sai Ma Department of Biology, MIT, Cambridge, MA, USA Broad Institute of MIT and Harvard, Cambridge, MA, USA Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA, USA PubMed articles Google scholar articles
Richard C Pelikan Genes and Human Disease Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, USA PubMed articles Google scholar articles
Yao Fu Genes and Human Disease Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, USA PubMed articles Google scholar articles
Jennifer A Kelly Genes and Human Disease Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, USA PubMed articles Google scholar articles
David Murphy Genes and Human Disease Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, USA PubMed articles Google scholar articles
Graham B Wiley Genes and Human Disease Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, USA PubMed articles Google scholar articles
Vinay K Kartha Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA, USA PubMed articles Google scholar articles
Caleb Lareau Department of Pathology, Stanford University, Stanford, CA, USA PubMed articles Google scholar articles
Jason D Buenrostro Broad Institute of MIT and Harvard, Cambridge, MA, USA Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA, USA PubMed articles Google scholar articles
Patrick M Gaffney Genes and Human Disease Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, USA PubMed articles Google scholar articles

Citation

Ma S, Pelikan RC, Fu Y, et al

1508 Single-cell epigenetic profiling highlights genetic impact on chromatin accessibility in SLE

Lupus Science & Medicine 2021;8:doi: 10.1136/lupus-2021-lupus21century.91

Publication history

First published November 4, 2021.

Online issue publication

January 09, 2022

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© Author(s) (or their employer(s)) 2021. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. http://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/.

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