Lupus Science & Medicine: 9 (1)

Brief communication

Cytokine autoantibodies in SARS-CoV-2 prepandemic and intrapandemic samples from an SLE cohort (7 April, 2022)
May Y Choi, Ann Elaine Clarke, Katherine Buhler, Michelle Jung, Hannah Mathew, Meifeng Zhang, Francesca S Cardwell, Heather Waldhauser, Marvin J Fritzler
LLDAS (lupus low disease activity state) and/or remission are associated with less damage accrual in patients with systemic lupus erythematosus from a primarily Mestizo population: data from the Almenara Lupus Cohort (22 February, 2022)
Manuel Francisco Ugarte-Gil, Rocio Violeta Gamboa-Cardenas, Cristina Reátegui-Sokolova, Victor Román Pimentel-Quiroz, Mariela Medina, Claudia Elera-Fitzcarrald, Francisco Zevallos, Cesar Augusto Pastor-Asurza, Jeniffer Lofland, Federico Zazzetti, Chetan S Karyekar, Graciela S Alarcón, Risto Alfredo Perich-Campos
Association of COVID-19 pandemic-related concern and health routine changes with functioning among individuals with systemic lupus erythematosus (17 February, 2022)
Laura C Plantinga, Courtney Hoge, Charmayne Dunlop-Thomas, Brad D Pearce, S Sam Lim, Cristina Drenkard, C Barrett Bowling

Biomarker studies

Original research: Novel immunoprofiling method for diagnosing SLE and evaluating therapeutic response (23 June, 2022)
Jan-Mou Lee, Ming-Huang Chen, Kai-Yuan Chou, Yee Chao, Ming-Han Chen, Chang-Youh Tsai
Original research:
Phenotypical changes and clinical significance of CD4⁺/CD8⁺ T cells in SLE
(22 June, 2022)
Shiwen Yuan, Yanting Zeng, Jiawei Li, Cuicui Wang, Weinian Li, Zhixiang He, Jinghua Ye, Fangfei Li, Yi Chen, Xiaojun Lin, Na Yu, Xiaoyan Cai
Original research: Predictors of treatment response in a lupus nephritis population: lessons from the Aspreva Lupus Management Study (ALMS) trial (31 May, 2022)
Stephen McDonald, Sean Yiu, Li Su, Caroline Gordon, Matt Truman, Laura Lisk, Neil Solomons, Ian N Bruce
Original research: Influence of hydroxychloroquine blood levels on adhesion molecules associated with endothelial dysfunction in patients with systemic lupus erythematosus (24 March, 2022)
Serena Fasano, Michele Iudici, Melania Alessia Coscia, Valentina Messiniti, Alessia Borgia, Rosella Tirri, Francesco Ciccia
Original research: Inflammatory markers in saliva and urine reflect disease activity in patients with systemic lupus erythematosus (4 March, 2022)
Guillermo Ruacho, Ronaldo Lira-Junior, Iva Gunnarsson, Elisabet Svenungsson, Elisabeth A Boström
Original research: Type 1 interferon status in systemic lupus erythematosus: a longitudinal analysis (23 February, 2022)
Melissa Northcott, Sarah Jones, Rachel Koelmeyer, Julie Bonin, Fabien Vincent, Rangi Kandane-Rathnayake, Alberta Hoi, Eric Morand

Childhood lupus

Original research: Clinical measurement of lupus nephritis activity is inferior to biomarker-based activity assessment using the renal activity index for lupus nephritis in childhood-onset systemic lupus erythematosus (13 May, 2022)
Najla Aljaberi, Scott E Wenderfer, Arjun Mathur, Tingting Qiu, Steffy Jose, Angela Merritt, James Rose, Prasad Devarajan, Bin Huang, Hermine Brunner
Original research: “There’s so much to be done”: a qualitative study to elucidate research priorities in childhood-onset systemic lupus erythematosus (31 March, 2022)
Laura Cannon, Anne Caliendo, Aimee Hersh, Andrea M Knight
Original research: Nailfold capillary scleroderma pattern may be associated with disease damage in childhood-onset systemic lupus erythematosus: important lessons from longitudinal follow-up (9 February, 2022)
Dieneke Schonenberg-Meinema, Sandy C Bergkamp, Amara Nassar-Sheikh Rashid, Mariken P Gruppen, Maritza A Middelkamp-Hup, Wineke Armbrust, Koert Dolman, A Elisabeth Hak, Petra C E Hissink Muller, Marieke van Onna, Joost F Swart, Taco W Kuijpers, Sylvia S M Kamphuis, Vanessa Smith, J Merlijn van den Berg

Clinical trials and drug discovery

Original research: Sirolimus versus tacrolimus for systemic lupus erythematosus treatment: results from a real-world CSTAR cohort study (3 January, 2022)
Nan Jiang, Mengtao Li, Hongfeng Zhang, Xinwang Duan, Xiaofeng Li, Yongfei Fang, Hongbin Li, Pingting Yang, Hui Luo, Yanhong Wang, Liying Peng, Jiuliang Zhao, Chanyuan Wu, Qian Wang, Xinping Tian, Yan Zhao, Xiaofeng Zeng

Co-morbidities

Original research: Red blood cell-derived phosphatidylserine positive extracellular vesicles are associated with past thrombotic events in patients with systemic erythematous lupus (8 March, 2022)
Stephan Hasse, Anne-Sophie Julien, Anne-Claire Duchez, Chenqi Zhao, Eric Boilard, Paul R Fortin, Sylvain G Bourgoin

Dialogue

Dialogue: Hydroxychloroquine pharmacokinetic (PK) and exposure response in pregnancies with systemic lupus erythematosus: the importance of adherence for neonatal outcome (7 January, 2022)
Bonnie Bermas, Nathalie Costedoat-Chalumeau

Epidemiology and outcomes

Original research: Impact of low-dose acetylsalicylic acid on pregnancy outcome in systemic lupus erythematosus: results from a multicentre study (14 June, 2022)
Chiara Tani, Dina Zucchi, Isabell Haase, Maria Gerosa, Maddalena Larosa, Lorenzo Cavagna, Alessandra Bortoluzzi, Francesca Crisafulli, Johanna Mucke, Francesca A L Strigini, Laura Baglietto, Marco Fornili, Francesca Monacci, Elena Elefante, Roberta Erra, Elisa Bellis, Melissa Padovan, Laura Andreoli, Lavinia Agra Coletto, Giovanni Zanframundo, Marcello Govoni, Luca Iaccarino, Angela Tincani, Andrea Doria, Rebecca Fischer-Betz, Marta Mosca
Original research: Glucocorticoid discontinuation in patients with SLE with prior severe organ involvement: a single-center retrospective analysis (2 June, 2022)
Takehiro Nakai, Sho Fukui, Yukihiko Ikeda, Masei Suda, Hiromichi Tamaki, Masato Okada
Original research: Real-world burden of systemic lupus erythematosus in the USA: a comparative cohort study from the Medical Expenditure Panel Survey (MEPS) 2016–2018 (24 May, 2022)
Shannon Grabich, Eileen Farrelly, Robert Ortmann, Michael Pollack, Sandra Sze-jung Wu
Original research: Predictors of refractory risk in systemic lupus erythematosus-related thrombocytopenia: a dual-centre retrospective study (20 May, 2022)
Kaisheng Su, Hao Cheng, Zhifang Jia, Yi Yuan, Huidan Yang, Qi Gao, Zhenyu Jiang, Hongyan Wen, Jing Jiang
Original research: Risk factors of disease flares in a Chinese lupus cohort with low-grade disease activity (20 May, 2022)
Fangfang Sun, Liling Zhao, Haiting Wang, Danting Zhang, Jie Chen, Xiaodong Wang, Ting Li, Shuang Ye
Original research: Improving patient pathways for systemic lupus erythematosus: a multistakeholder pathway optimisation study (13 May, 2022)
Aurelien Schlencker, Laurent Messer, Marc Ardizzone, Gilles Blaison, Olivier Hinschberger, Etienne Dahan, Christelle Sordet, Julia Walther, Anne Dory, Maria Gonzalez, Stéphanie Kleinlogel, Aurélia Bramont-Nachman, Lionel Barrand, Isabelle Payen-Revol, Jean Sibilia, Thierry Martin, Laurent Arnaud
Original research: Coping with systemic lupus erythematosus in patients’ words (13 May, 2022)
Alain Cornet, Davide Mazzoni, Angela Edwards, Dario Monzani, Gabriella Pravettoni, Jeanette Andersen, Marta Mosca
Original research: Severe flares are associated with a poorer health-related quality of life (HRQoL) in patients with SLE: data from the Almenara Lupus Cohort (29 March, 2022)
Manuel Francisco Ugarte-Gil, Rocio Violeta Gamboa-Cardenas, Cristina Reátegui-Sokolova, Victor Román Pimentel-Quiroz, Mariela Medina, Claudia Elera-Fitzcarrald, Francisco Zevallos, Cesar Augusto Pastor-Asurza, Federico Zazzetti, Chetan S Karyekar, Graciela S Alarcón, Risto Alfredo Perich-Campos
Original research: Clinical and histopathological features of myositis in systemic lupus erythematosus (29 March, 2022)
Eleni Tiniakou, Daniel Goldman, Andrea Corse, Andrew Mammen, Michelle A Petri
Original research: Flare rates and factors determining flare occurrence in patients with systemic lupus erythematosus who achieved low disease activity or remission: results from a prospective cohort study (3 March, 2022)
Yanjie Hao, Lanlan Ji, Dai Gao, Yong Fan, Yan Geng, Xiaohui Zhang, Guangtao Li, Zhuoli Zhang
Original research: Assessing the validity of QRISK3 in predicting cardiovascular events in systemic lupus erythematosus (22 February, 2022)
Lisa Zhu, Manpreet Singh, Sonia Lele, Lori Sahakian, Jennifer Grossman, Bevra Hahn, Maureen McMahon
Original research: Cross-sectional study of the effects of self-efficacy on fatigue and pain interference in black women with systemic lupus erythematosus: the role of depression, age and education (11 February, 2022)
Cristina Drenkard, Kirk Easley, Gaobin Bao, Charmayne Dunlop-Thomas, S Sam Lim, Teresa Brady
Original research: Herpes zoster in SLE: prevalence, incidence and risk factors (11 January, 2022)
Andrew Kwan, Hanan Al Rayes, Tijana Lazova, Nicole Anderson, Dennisse Bonilla, Jiandong Su, Zahi Touma
Original research: Risk factors of flare in patients with systemic lupus erythematosus after glucocorticoids withdrawal. A systematic review and meta-analysis (7 January, 2022)
Lanlan Ji, Wenhui Xie, Serena Fasano, Zhuoli Zhang

Genetics

Original research: Human leucocyte antigens profiling in Malay female patients with systemic lupus erythematosus: are we the same or different? (1 February, 2022)
Malarvili Selvaraja, Chun Lai Too, Lay Kim Tan, Bee Tee Koay, Maha Abdullah, Anim Md Shah, Masita Arip, Syafinaz Amin-Nordin

Immunology and inflammation

Original research: Role of autoantibodies and blood–brain barrier leakage in cognitive impairment in systemic lupus erythematosus (15 June, 2022)
John G Hanly, Alexandra Legge, Lyna Kamintsky, Alon Friedman, Javeria A Hashmi, Steven D Beyea, John Fisk, Antonina Omisade, Cynthia Calkin, Tim Bardouille, Chris Bowen, Kara Matheson, Marvin J Fritzler
Original research: Association between systemic lupus erythematosus and disruption of gut microbiota: a meta-analysis (28 March, 2022)
Shate Xiang, Yiqian Qu, Suhai Qian, Rongyun Wang, Yao Wang, Yibo Jin, Jie Li, Xinghong Ding
Original research: Iberdomide in patients with systemic lupus erythematosus: a randomised, double-blind, placebo-controlled, ascending-dose, phase 2a study (15 February, 2022)
Richard A Furie, Douglas R Hough, Allison Gaudy, Ying Ye, Shimon Korish, Nikolay Delev, Michael Weiswasser, Xiaojiang Zhan, Peter H Schafer, Victoria P Werth
Original research: Reductions in circulating B cell subsets and immunoglobulin G levels with long-term belimumab treatment in patients with SLE (7 February, 2022)
Herbert Struemper, Milena Kurtinecz, Lisa Edwards, William W Freimuth, David A Roth, William Stohl

Letter

Activation-induced colocalisation of SCAMP5 with IFNα in human plasmacytoid dendritic cells (16 March, 2022)
Juliëtte N Pouw, Michel A M Olde Nordkamp, Tom G O'Toole, Timothy R D J Radstake, Emmerik F A Leijten, Marianne Boes
To treat or not to treat with immunosuppressive therapy: psychiatric disorders in patients with systemic lupus erythematosus (7 January, 2022)
Rory C Monahan, Anne M E Blonk, Tom WJ Huizinga, Margreet Kloppenburg, Huub A M Middelkoop, Nic J A van der Wee, Gerda M Steup-Beekman

Lupus nephritis

Original research:
Characteristics and renal survival of patients with lupus nephritis with glomerular immunoglobulin G₄ deposition: a single-centre retrospective analysis
(16 June, 2022)
Xue Jiang, Lan Lan, Qin Zhou, Huijing Wang, Huiping Wang, Jianghua Chen, Fei Han
Original research: Clinical and histological findings at second but not at first kidney biopsy predict end-stage kidney disease in a large multicentric cohort of patients with active lupus nephritis (13 May, 2022)
Mariele Gatto, Francesca Radice, Francesca Saccon, Marta Calatroni, Giulia Frontini, Barbara Trezzi, Margherita Zen, Anna Ghirardello, Francesco Tamborini, Valentina Binda, Vincenzo L'Imperio, Andrea Doria, Augusto Vaglio, Renato Alberto Sinico, Gabriella Moroni, Luca Iaccarino
Original research: One-third of patients with lupus nephritis classified as complete responders continue to accrue progressive renal damage despite resolution of proteinuria (5 May, 2022)
Emma Weeding, Andrea Fava, Laurence Magder, Daniel Goldman, Michelle Petri
Original research: Metformin improves renal injury of MRL/lpr lupus-prone mice via the AMPK/STAT3 pathway (12 April, 2022)
Xiao-cui Chen, Dan Wu, Hong-luan Wu, Hui-yuan Li, Chen Yang, Hong-yong Su, Ze-jian Liu, Xiao-rong Huang, Xing Lu, Li-feng Huang, Shao-ping Zhu, Qing-jun Pan, Ning An, Hua-feng Liu
Original research: Immune gene expression and functional networks in distinct lupus nephritis classes (24 January, 2022)
Alyssa C Gilmore, Hannah R Wilson, Thomas D Cairns, Marina Botto, Liz Lightstone, Ian N Bruce, Herbert Terence Cook, Matthew Caleb Pickering
Original research: Membrane attack complex (MAC) deposition in renal tubules is associated with interstitial fibrosis and tubular atrophy: a pilot study (7 January, 2022)
Shudan Wang, Ming Wu, Luis Chiriboga, Briana Zeck, Beatrice Goilav, Shuwei Wang, Alejandra Londono Jimenez, Chaim Putterman, Daniel Schwartz, James Pullman, Anna Broder, H Michael Belmont

Protocol

Low-dose belimumab for patients with systemic lupus erythematosus at low disease activity: protocol for a multicentre, randomised, double-blind, placebo-controlled clinical trial (1 February, 2022)
Fangfang Sun, Wenyan Huang, Jie Chen, Liling Zhao, Danting Zhang, Xiaodong Wang, Weiguo Wan, Sheng-Ming Dai, Sheng Chen, Ting Li, Shuang Ye

Reproductive health and APS

Original research: Pregnancy outcomes in antiphospholipid antibody positive patients: prospective results from the AntiPhospholipid Syndrome Alliance for Clinical Trials and InternatiOnal Networking (APS ACTION) Clinical Database and Repository (‘Registry’) (14 June, 2022)
Zeynep Belce Erton, Ecem Sevim, Guilherme Ramires de Jesús, Ricard Cervera, Lanlan Ji, Vittorio Pengo, Amaia Ugarte, Danieli Andrade, Laura Andreoli, Tatsuya Atsumi, Paul R Fortin, Maria Gerosa, Yu Zuo, Michelle Petri, Savino Sciascia, Maria G Tektonidou, Maria Angeles Aguirre- Zamorano, D Ware Branch, Doruk Erkan
Original research: Hydroxychloroquine in the pregnancies of women with lupus: a meta-analysis of individual participant data (21 March, 2022)
Megan E B Clowse, Amanda M Eudy, Stephen Balevic, Gillian Sanders-Schmidler, Andrzej Kosinski, Rebecca Fischer-Betz, Dafna D Gladman, Yair Molad, Cecilia Nalli, Abir Mokbel, Angela Tincani, Murray Urowitz, Caroline Bay, Megan van Noord, Michelle Petri
Original research: Impact of pregnancy in patients with systemic lupus erythematosus-associated pulmonary arterial hypertension: case series and literature review (7 March, 2022)
Mucong Li, Zhuang Tian, Junyan Qian, Can Huang, Jiuliang Zhao, Qian Wang, Yijun Song, Xinping Tian, Mengtao Li, Juntao Liu, Xiaofeng Zeng
Original research: Hydroxychloroquine PK and exposure-response in pregnancies with lupus: the importance of adherence for neonatal outcomes (7 January, 2022)
Stephen J Balevic, Daniel Weiner, Megan E B Clowse, Amanda M Eudy, Anil R Maharaj, Christoph P Hornik, Michael Cohen-Wolkowiez, Daniel Gonzalez

Review

Conceptual framework for defining disease modification in systemic lupus erythematosus: a call for formal criteria (28 March, 2022)
Ronald van Vollenhoven, Anca D Askanase, Andrew S Bomback, Ian N Bruce, Angela Carroll, Maria Dall'Era, Mark Daniels, Roger A Levy, Andreas Schwarting, Holly A Quasny, Murray B Urowitz, Ming-Hui Zhao, Richard Furie
Central nervous system infections in patients with systemic lupus erythematosus: a systematic review and meta-analysis (3 January, 2022)
Kasra Molooghi, Fereshte Sheybani, Hamidreza Naderi, Zahra Mirfeizi, Negar Morovatdar, Ashkan Baradaran

Correction

Correction: 2021 DORIS definition of remission in SLE: final recommendations from an international task force (7 February, 2022)

Main menu

Current Issue

2022 - Volume 9 - 1

Brief communication

Biomarker studies

Childhood lupus

Clinical trials and drug discovery

Co-morbidities

Dialogue

Epidemiology and outcomes

Genetics

Immunology and inflammation

Letter

Lupus nephritis

Protocol

Reproductive health and APS

Review

Correction

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Current Issue

2022 - Volume 9 - 1

Brief communication

Biomarker studies

Childhood lupus

Clinical trials and drug discovery

Co-morbidities

Dialogue

Epidemiology and outcomes

Genetics

Immunology and inflammation

Letter

Lupus nephritis

Protocol

Reproductive health and APS

Review

Correction