RT Journal Article
SR Electronic
T1 Predictors of peripheral arterial disease in SLE change with patient’s age
JF Lupus Science & Medicine
FD Lupus Foundation of America
SP e000190
DO 10.1136/lupus-2016-000190
VO 4
IS 1
A1 Erdozain, Jose-Gabriel
A1 Villar, Irama
A1 Nieto, Javier
A1 Ruiz-Arruza, Ioana
A1 Ruiz-Irastorza, Guillermo
YR 2017
UL http://lupus.bmj.com/content/4/1/e000190.abstract
AB Objective To analyse the differential influence of risk factors of peripheral artery disease (PAD) according to age in patients with SLE.Methods 216 patients from the Lupus-Cruces cohort were divided in three age groups: ≤34 years, 35–49 years and ≥50 years. A low ankle–brachial index defined PAD. Significant variables were identified by univariant and multivariant analysis in each age group.Results Different factors were identified in different age groups: antiphospholipid antibodies/antiphospholipid syndrome and glucocorticoids in patients ≤34 years; in patients 35–49 years old, hypertension was the only statistically significant predictor, although a trend was observed for fibrinogen levels; a trend was observed for hypercholesterolaemia in those ≥50 years.Conclusions Age may modulate the influence of risk factors for PAD in patients with SLE.