Association between most relevant clinical manifestations and positive outcome of anti-dsDNA tests (any CLIFT and any ELISA)
| Any CLIFT positive (39 ANA positive+20 ANA negative) | Any ELISA positive (50 ANA positive+49 ANA negative) | |||
|---|---|---|---|---|
| CRUDE OR (95% CI) | ADJUSTED OR (95% CI) | CRUDE OR (95% CI) | ADJUSTED OR (95% CI) | |
| Peripheral arthritis | 1.1 (0.6–2) | 0.6 (0.4–1.04) | ||
| Photosensitivity | 0.6 (0.2–1.7) | 0.5 (0.2–1.2) | ||
| Oral ulcers | 0.8 (0.25–2.9) | 1.8 (0.8–4.1) | ||
| Haematuria | 3.8 (1.4–10.4) | 0.6 (0.1–3.4) | 3.2 (1.3–8) | 0.5 (0.1–2.8) |
| Proteinuria | 14 (5.1–38.4) | 13 (2.9–57.7) | 16.7 (5.3–52.6) | 18.8 (3.7–95.2) |
| Malar rash | 3.1 (0.97–10.2) | 1.7 (0.5–5.4) | ||
| Anaemia | 3.8 (1.4–10.4) | 1.1 (0.4–3.5) | ||
| Leukopenia | 6.8 (2.3–20.3) | 2.3 (0.5–10.7) | 6.5 (2.2–19.1) | 3.5 (0.8–14.2) |
| Alopecia | 4.4 (1.3–15) | 4.3 (1.1–16) | 3.35 (1–10.8) | 3.1 (0.9–10.8) |
| Lymphopenia | 10.9 (3.2–37) | 2.7 (0.8–9.2) | ||
| Discoid LE | 1.2 (0.1–9.8) | 0.6 (0.8–5.3) | ||
| Thrombocytopenia | 8.8 (2.1–36.2) | 3.1 (0.5–20.2) | 4.7 (1.1–19) | 1.1 (0.2–7.6) |
| Pleuritis | 13 (2.1–79.6) | 11.1 (1.5–83.8) | 18.8 (2.1–170.3) | 14.5 (1.4–148.2) |
| Arthralgia | 0.6 (0.3–1.02) | 0.5 (0.3–0.8) | ||
| Morning joint stiffness | 0.5 (0.2–1.04) | 0.4 (0.2–0.7) | ||
| Raynaud's phenomenon | 1.6 (0.8–3.2) | 1.2 (0.6–2.2) | ||
| Headache | 0.7 (0.3–1.75) | 0.8 (0.4–1.6) | ||
| Xerostomia | 0.75 (0.3–1.8) | 1 (0.5–2) | ||
| Arterial hypertension | 0.96 (0.4–2.2) | 1 (0.5–1.9) | ||
| Tendinitis | 0.2 (0.02–1.2) | 1.3 (0.7–2.7) | ||
| Psoriasis | 0.6 (0.2–2.2) | 0.5 (0.2–1.4) | ||
| Affective disorder | 0.7 (0.2–2.2) | 0.8 (0.3–1.9) | ||
| Keratoconjunctivitis sicca | 0.4 (0.1–1.8) | 0.8 (0.3–2) | ||
| Cutaneous vasculitis | 6.7 (2.25–20.2) | 2.1 (0.5–9.4) | 6.4 (2.2–18.9) | 2.4 (0.6–9.5) |
| Asthma or COL | 2.4 (1.04–5.5) | 1.4 (0.7–3.15) | ||
| Lymphadenopaty | 6.5 (1.4–29.7) | 1.8 (0.3–9.6) | ||
Crude OR with corresponding 95% CIs in brackets is reported for all the variables. Adjusted OR is reported only for variables significantly associated with positivity of any CLIFT and any ELISA.
ANA, antinuclear antibodies; CLIFT, Crithidia Lucillia Immunofluorescence Test.