1993* | 1996 | 1999 | 2002 | 2004 | 2007 | 2010 | 2012 | |
---|---|---|---|---|---|---|---|---|
N | 1249 | 1359 | 1701 | 1369 | 1040 | 846 | 986 | 914 |
Sex, female (%) | 90 | 90 | 89 | 88 | 89 | 89 | 89 | 90 |
Mean age, years | 42.4 | 42.8 | 44.2 | 45.0 | 46.1 | 45.8 | 45.6 | 46.4 |
Mean disease duration, years | 9.2 | 9.0 | 9.4 | 10.1 | 10.8 | 11.9 | 13.1 | 14.0 |
Mean age at disease onset, years. | 31.2 | 32.0 | 33.0 | 32.6 | 33.0 | 32.2 | 31.0 | 30.7 |
Disease severity†, (%) asymptomatic/mild | 46.4 | 45.3 | 49.4 | 43.5 | 40.7 | 44.7 | 45.5 | 46.1 |
Moderate | 38.4 | 38.6 | 36.4 | 41.6 | 41.5 | 44.6 | 43.1 | 41.8 |
(Very) Severe | 15.2 | 16.1 | 14.1 | 14.9 | 17.8 | 10.7 | 11.4 | 12.1 |
*For better readability, only data of every second to third year is shown.
†The disease severity was assessed by the physician.