ORs and 95% CIs for adverse pregnancy outcomes occurring before and after SLE diagnosis compared with controls in an African-American population
Stillbirth | Spontaneous abortion | Elective abortion | Preterm live birth | Low birth weight | Preeclampsia | |
---|---|---|---|---|---|---|
Controls | n=5 | n=64 | n=21 | n=29 | n=28 | n=29 |
(694 pregnancies) | 1.00 (reference) | 1.00 (reference) | 1.00 (reference) | 1.00 (reference) | 1.00 (reference) | 1.00 (reference) |
Cases | n=16 | n=102 | n=22 | n=66 | n=58 | n=45 |
(all) | 4.43 | 2.20 | 1.20 | 2.45 | 2.62 | 1.70 |
(577 pregnancies) | (1.61 to 12.17)*† | (1.58 to 3.08)* | (0.63 to 2.29)† | (1.43 to 4.17)* | (1.52 to 4.52)* | (0.98 to 2.94) |
Cases | n=9 | n=41 | n=8 | n=30 | n=31 | n=28 |
(before diagnosis) | 3.90 | 1.37 | 0.83 | 1.87 | 2.01 | 1.80 |
(337 pregnancies) | (1.30 to 11.76)*† | (0.87 to 2.18) | (0.36 to 1.89)† | (1.07 to 3.28)* | (1.14 to 3.54)* | (1.03 to 3.16)* |
Cases | n=5 | n=39 | n=5 | n=26 | n=22 | n=14 |
(after diagnosis) | 6.15 | 2.79 | 1.47 | 4.70 | 5.48 | 2.03 |
(147 pregnancies) | (1.75 to 21.65)*† | (1.61 to 4.81)* | (0.54 to 3.98)† | (2.42 to 9.13)* | (2.81 to 10.69)* | (0.94 to 4.39) |
Cases | n=2 | n=22 | n=9 | n=10 | n=5 | n=3 |
(unknown order) | 4.02 | 2.96 | 4.31 | 4.62 | 2.39 | 1.32 |
(93 pregnancies) | (0.76 to 21.17)† | (1.59 to 5.48)* | (1.89 to 9.82)*† | (2.10 to 10.16)*† | (0.89 to 6.52)† | (0.38 to 4.50)† |
All estimates are adjusted for age, years of education, insurance and pregnancy number.
*p<0.05.
†Unadjusted model.
SLE, systemic lupus erythematosus.