Sensitivity, specificity, PPV and NPV for good long-term renal outcome according to target definition
| Target at 12 months | Sensitivity (%) | Specificity (%) | PPV (%) | NPV (%) |
|---|---|---|---|---|
| Proteinuria <0.7 g/day | 71 (48/68) | 75 (9/12) | 94 (48/51) | 31 (9/29) |
| Proteinuria <0.7 g/day and sCr ≤1 mg/dL | 63 (43/68) | 83 (10/12) | 96 (43/45) | 29 (10/31) |
| Proteinuria <0.7 g/day and sCr ≤1 mg/dL and RBC ≤5/hpf | 41 (28/68) | 67 (8/12) | 97 (28/29) | 21 (8/38) |
Figures in brackets are number of patients: for the sensitivity, patients with good outcome among those achieving the target/total patients with good outcome; for the specificity, patients with poor outcome among those not achieving the target/total patients with poor outcome; for the PPV, patients with good outcome/target achievers; for the NPV, patients with poor outcome/target non-achievers. Of note, only 80 of the 90 patients had proteinuria values available at month 12.
hpf, high power field; NPV, negative predictive value; PPV, positive predictive value; RBC, red blood cells; sCr, serum creatine.