Association between subclinical cardiovascular disease imaging of the coronary and carotid arteries in patients with SLE with and without adverse pregnancy outcomes
| Adverse pregnancy outcomes | No adverse pregnancy outcomes | OR (95% CI) Age and disease duration adjusted | |
|---|---|---|---|
| CAC score≥10, n (%) | 14/54*(25.9) | 13/73 (17.8) | 1.5 (0.6 to 3.9) |
| Carotid plaque=1, n (%) | 26/56 (46.4) | 28/73 (38.4) | 1.5 (0.7 to 3.2) |
| Pre-eclampsia | No adverse pregnancy outcomes | ||
| CAC score≥10, n (%) | 10/26 (38.5) | 13/73 (17.8) | 3.7 (1.2 to 11.9) |
| Carotid plaque=1, n (%) | 10/26 (38.5) | 28/73 (38.4) | 1.1 (0.4 to 2.8) |
| Low birthweight infant | No adverse pregnancy outcomes | ||
| CAC score≥10, n (%) | 8/27*(30.0) | 13/73 (17.8) | 2.2 (0.7 to 7.4) |
| Carotid plaque=1, n (%) | 14/28 (50.0) | 28/73 (38.4) | 2.0 (0.8 to 5.1) |
| Preterm birth | No adverse pregnancy outcomes | ||
| CAC score≥10, n (%) | 8/35*(22.9) | 13/73 (17.8) | 1.0 (0.3 to 3.2) |
| Carotid plaque=1, n (%) | 18/36 (50.0) | 28/73 (38.4) | 1.6 (0.7 to 3.8) |
Adverse pregnancy outcomes include pre-eclampsia, low birthweight infants or preterm birth.
*Two women with adverse pregnancy outcomes (one each preterm and low birth weight) did not have a coronary calcium score calculated.
CAC, coronary artery calcium; SLE, systemic lupus erythematosus.