Reasons of AD admission to ICU
| Characteristic | Total | Poly AD | SLE | SSc | RA | APS | SV | DPM | SS | AIH | AITD | PEN | PRS |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| (n=50) | (n=13) | (n=23) | (n=10) | (n=9) | (n=6) | (n=7) | (n=3) | (n=3) | (n=2) | (n=3) | (n=2) | (n=1) | |
| Infection | 18 (36) | 5 (38.46) | 10 (45.45) | 3 (30) | 5 (55.56) | 2 (33.3) | 1 (16.67) | – | 1 (33.33) | 1 (50) | – | – | – |
| AD flare-up | 12 (24) | 2 (15.38) | 3 (16.64) | 1 (10)* | – | – | 4 (57.4) | 3 (100) | 1 (33.33) | 1 (50) | − | 1 (50) | 1 (100) |
| AD complication | 10 (20) | 3 (23.08) | 3 (13.64) | 4 (40) | 1 (11,11) | 2 (33.3) | – | – | 1 (33.33) | – | 2 (66.66) | 1 (50) | – |
| Adverse drug effect | 2 (4) | 1 (7.69) | – | 1 (10)† | 1 (11.11) | 1 (16.67) † | 1 (16.67)† | – | – | – | – | – | – |
| Not related to AD‡ | 8 (16) | 2 (15.38) | 7 (30.43) | 1 (10) | 2 (22.22) | 1 (16.67) | 1 (16.67) | – | – | – | 1 (33.33) | – | – |
*Polyautoimmunity was the cause of admission in SSc due to flare up of SLE.
†Cause of admission due to warfarin over-anticoagulation in a patient with polyautoimmunity. There were 50 patients with at least one AD; from this group 13 patients (26%) presented at least one other AD (ie, polyautoimmunity). A total of 69 ADs were reported and the cause of ICU admission related with kind of ADs. All patients with AD met the international classification criteria.22
‡Infection excluded.
AD, autoimmune disease; AIH, Autoimmune hepatitis; AITD: autoimmune thyroid disease; APS, Antiphospholipid Syndrome; DPM, dermatopolymyositis; PEN, immunological cytopenia (autoimmune haemolytic anaemia, primary immune thrombocytopenia); PRS, pulmonary renal syndrome; RA, Rheumatoid Arthritis; SLE, Systemic Lupus Erythematosus; SS, Sjögren syndrome; SSc, Systemic Scleroderma; SV, systemic vasculitis.