Brain region | Coordinates*† | |||
---|---|---|---|---|
Zmax | x | y | z | |
(A) Metabolic increases in SLE compared with HC | ||||
Hippocampus | ||||
Right | 4.01 | 24 | −22 | −10 |
Left | 3.32 | −28 | −28 | 0 |
Orbitofrontal cortex, BA 11 | ||||
Right | 3.54 | 28 | 38 | −14 |
Left | 4.35 | −22 | 40 | −14 |
Putamen/globus pallidus, right | 3.79 | 26 | −26 | 0 |
(B) Metabolic decreases in LT-SLE compared with ST-SLE | ||||
Prefrontal cortex, BA 9, left | 3.66 | −20 | 42 | 20 |
Prefrontal cortex, BA 10, left | 3.92 | −10 | 58 | 10 |
Premotor cortex, BA 6, left | 3.37 | −24 | 8 | 48 |
*Montreal Neurological Institute standard space.55
†p<0.001, uncorrected; p<0.05, corrected for cluster extent.
BA, Brodmann area; HC, healthy controls; LT, long term; SLE, systemic lupus erythematosus; ST, short term.