No OP (134) | With OP (52) | With FFx (22) | p value | |
---|---|---|---|---|
Female/male | 128/6 | 47/5 | 22/0 | NA |
Mean age at last observation | 42.3±10.9 years | 56.9±12 years | 61.3±10.3 years | <0.0001* |
Mean disease duration | 16.5±7.7 years | 22.5±8 years | 23.4±7.1 years | <0.01* |
Cutaneous involvement | 108/134 (80.6%) | 19/52 (36.5%) | 8/22 (36.4%) | Ns |
Joint involvement | 97/134 (72.4%) | 18/52 (34.6%) | 12/22 (54.5%) | Ns |
CNS involvement | 34/134 (25.4%) | 13/52 (25%) | 6/22 (27.3%) | Ns |
Renal involvement | 71/134 (53%) | 30/52 (57.7%) | 14/22 (63.6%) | Ns |
Chronic renal failure | 14/134 (10.4%) | 12/52 (23.1%) | 6/22 (27.3%) | <0.05* |
*OP and FFx versus no OP.
CNS, central nervous system; FFx, fragility fractures; OP, osteoporosis.