Table 6

Joint relationship between combinations of elevated IgG aCL and elevated RVVT and risk of thrombosis

Antibody combinationsSubgroup*No. of thrombosesNo. of person-yearsRate (per 1000)Rate ratiosp Value
aCL IgG
RVVT
Neither elevated (n=1246)22815 35114.91.0 (Ref. group)
Elevated IgG but not elevated RVVT (n=41)1747435.92.4 (1.4, 3.9)0.0006
Elevated RVVT but not elevated IgG (n=72)3182537.62.4 (1.7, 3.6)<0.0001
Both
elevated (n=31)
837621.31.4 (0.7, 2.8)0.36
  • *‘Elevated’ IgG means a geometric mean titre of ≥20. ‘Elevated’ RVVT means an RVVT of ≥45.

  • RVVT, dilute Russell's viper venom time.