Characteristics of the Georgians Organized Against Lupus cohort of patients with SLE in September 2013–November 2014, overall and by categorised age at survey
| Age at survey, years | ||||||
|---|---|---|---|---|---|---|
| Characteristic | N | Overall | 20–39 N=198 (29.0%) | 40–59 N=362 (52.9%) | ≥60 N=124 (18.1%) | p Value* |
| Sociodemographic | ||||||
| Mean (SD) age at survey | 684 | 47.8 (13.0) | 32.3 (5.1) | 49.8 (5.7) | 66.9 (5.7) | <0.001 |
| % Male | 684 | 5.6% | 5.6% | 5.8% | 4.8% | 0.92 |
| Race, % | 684 | 0.16 | ||||
| White | 19.6% | 19.2% | 18.0% | 25.0% | ||
| African-American | 78.5% | 77.3% | 81.0% | 74.2% | ||
| Other | 1.9% | 3.5% | 1.4% | 0.8% | ||
| % Hispanic/Latino | 680 | 5.0% | 7.1% | 4.7% | 2.4% | 0.16 |
| Marital status, % | 684 | <0.001 | ||||
| Never married | 32.5% | 58.1% | 26.26% | 9.7% | ||
| Married | 32.6% | 18.2% | 37.1% | 42.7% | ||
| Separated, divorced, widowed | 34.9% | 23.7% | 36.7% | 47.6% | ||
| Mean (SD) years of education | 673 | 14.6 (3.1) | 14.6 (2.9) | 14.6 (3.0) | 14.9 (3.5) | 0.64 |
| Employment, % | 684 | <0.001 | ||||
| Employed | 37.3% | 45.0% | 38.7% | 21.0% | ||
| Not employed† | 24.9% | 19.2% | 16.9% | 57.3% | ||
| Disabled | 37.9% | 35.9% | 44.5% | 21.8% | ||
| Income, % | 630 | <0.001 | ||||
| <US$20 000 | 41.1% | 47.6% | 42.9% | 24.6% | ||
| US$20 000–$49 999 | 27.0% | 30.2% | 22.7% | 34.6% | ||
| ≥US$50 000 | 31.9% | 22.2% | 34.4% | 40.9% | ||
| % Always/usually have emotional support | 684 | 56.7% | 57.6% | 53.3% | 65.3% | 0.06 |
| Clinical | ||||||
| Mean (SD) age at onset | 684 | 32.4 (12.2) | 21.8 (6.1) | 33.8 (9.5) | 45.3 (11.8) | <0.001 |
| Age at onset, % | 684 | <0.001 | ||||
| Paediatric (<18 years) | 10.5% | 26.3% | 4.7% | 2.4% | ||
| Early adult (18–49 years) | 81.0% | 73.7% | 91.7% | 61.3% | ||
| Late adult (≥50 years) | 8.5% | 0.0% | 3.6% | 36.3% | ||
| Mean (SD) duration of SLE, years | 684 | 15.4 (9.6) | 10.5 (5.9) | 15.9 (9.3) | 21.6 (11.3) | <0.001 |
| % SLE onset within past 10 years | 684 | 33.6% | 49.5% | 31.2% | 15.3% | <0.001 |
| Mean (SD) BMI | 644 | 29.3 (7.8) | 28.1 (7.7) | 30.0 (8.1) | 29.3 (6.8) | 0.03 |
| Renal involvement‡, % | 633 | 30.2% | 41.5% | 27.7% | 21.3% | <0.001 |
| Median (IQR) PHQ-9 score | 683 | 7 (3–12) | 7 (3–12) | 8 (4–13) | 6 (2–10) | 0.004 |
| Median (IQR) BILD score | 684 | 3 (1–5) | 2 (1–3) | 3 (1–5) | 4 (2–5) | <0.001 |
| Median (IQR) SLAQ score | 684 | 15 (9–23) | 15 (9–23) | 17 (10–24) | 15 (8–20) | 0.22 |
| Mean (SD) LIT score | 682 | 41.8 (24.1) | 40.9 (24.0) | 43.9 (24.4) | 37.1 (22.6) | 0.02 |
*By χ2, Fisher's exact, analysis of variance or non-parametric equality-of-medians test, as appropriate.
†Includes retired, student and homemaker population.
‡From American College of Rheumatology diagnostic criteria.
BILD, Brief Index of Lupus Damage; BMI, body mass index; LIT, Lupus Impact Tracker; PHQ-9, nine-item Patient Health Questionnaire; SLAQ, Systemic Lupus Activity Questionnaire; SLE, systemic lupus erythematosus.